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How to get fromKnoxville to Kissimmeeby plane, taxi, bus (Greyhound, Flixbus), car, shuttle, bus, or train

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There are 7 ways to get from Knoxville to Kissimmee by plane, taxi, bus (Greyhound, Flixbus), car, shuttle, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mcghee Tyson Airport to Orlando Sanford, taxi

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Orlando Sanford (SFB)plane plane TYS - SFB
    2. Take the taxi from Orlando-Sanford-Airport-SFB to Kissimmeetaxi taxi
    2h 49m
    $242–687

  2. Drive 644.9 mi

    cheapest
    1. Drive from Knoxville to Kissimmeecar car 644.9 mi
    10h 54m
    $118–170

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Orlandobus bus
    20h 35m
    $240–376

  4. Drive, shuttle, taxi, bus, train

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Boonetaxi taxi
    4. Take the bus from Boone to Forsyth Hospitalbus bus
    5. Take the train from High Point to Carytrain train
    6. Take the train from Cary to Kissimmee Amtrak Stationtrain train
    26h 38m

  5. Fly Mcghee Tyson Airport to Orlando

    1. Fly from Mcghee Tyson Airport (TYS) to Orlando (MCO)plane plane TYS - MCO
    3h 25m
    $146–553

  6. Drive to Asheville Regional Airport, fly to Orlando Sanford, taxi

    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Orlando Sanford (SFB)plane plane AVL - SFB
    3. Take the taxi from Orlando-Sanford-Airport-SFB to Kissimmeetaxi taxi
    4h 40m
    $177–492

  7. Drive, shuttle, bus

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    4. Take the bus from Boone to Charlottebus bus
    5. Take the bus from Charlotte Bus Station to Orlando Bus Stationbus bus
    22h 21m

Mcghee Tyson Airport (TYS) to Orlando Sanford (SFB) flights

Calendar12Weekly Planes
Duration1h 36mAverage Duration
Ticket$89Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Kissimmee.ExpandLaunch map view
  • Distance: 562.1 mi
  • Duration: 2h 49m

What companies run services between Knoxville, TN, USA and Kissimmee, FL, USA?

You can take a vehicle from Knoxville to N Main St & W Cypress St via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, Atlanta Bus Station, Orlando, and Florida Mall in around 20h 35m. Alternatively, Allegiant Air, Southwest Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Orlando (MCO) every 4 hours.

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