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How to get fromKnoxville to La Grangeby plane, bus, bus (Amtrak, Greyhound), car, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Knoxville to La Grange by plane, bus, bus (Amtrak, Greyhound), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mcghee Tyson Airport to Chicago O'Hare International Airport, line 330 bus

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Chicago O'Hare International Airport (ORD)plane plane TYS - ORD
    2. Take the bus from Rosemont CTA Station to La Grange/47thbus bus
    3h 26m
    $126–475

  2. Drive to Chattanooga Metropolitan Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Drive from Knoxville to Chattanooga Metropolitan Airport (CHA)car car
    2. Fly from Chattanooga Metropolitan Airport (CHA) to Chicago O'Hare International Airport (ORD)plane plane CHA - ORD
    5h 2m
    $73–325

  3. Bus via La Grange/47th

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville to Chicago Union Stationbus bus
    15h 53m
    $208–317

  4. Drive 530.6 mi

    1. Drive from Knoxville to La Grangecar car 530.6 mi
    9h 28m
    $97–140

  5. Fly Mcghee Tyson Airport to Chicago Midway International Airport, line 330 bus

    1. Fly from Mcghee Tyson Airport (TYS) to Chicago Midway International Airport (MDW)plane plane TYS - MDW
    2. Take the bus from Archer/72nd Ct. to La Grange/47thbus bus
    3h 21m
    $141–543

  6. Drive to Asheville Regional Airport, fly to Chicago O'Hare International Airport

    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Chicago O'Hare International Airport (ORD)plane plane AVL - ORD
    5h 28m
    $76–340

  7. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Chicago Bus Stationbus bus Greyhound US0100
    16h 1m
    $207–314

Mcghee Tyson Airport (TYS) to Chicago O'Hare International Airport (ORD) flights

Calendar87Weekly Planes
Duration3h 13mAverage Duration
Ticket$69Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to La Grange.ExpandLaunch map view
  • Distance: 504.5 mi
  • Duration: 3h 26m

What companies run services between Knoxville, TN, USA and La Grange, Cook County, IL, USA?

You can take a vehicle from Knoxville to La Grange/47th via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville, Chicago Union Station, Chicago Union Station, LaGrange Road, and La Grange/Hillgrove/Metra Station in around 15h 53m.

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