There are 4 ways to get from Knoxville to Lake Charles by plane, bus (Flixbus), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Lake Charles Regional Airport
best- Fly from Mcghee Tyson Airport (TYS) to Lake Charles Regional Airport (LCH)plane TYS - LCH
5h 24m$188–730Drive 757.1 mi
cheapest- Drive from Knoxville to Lake Charlescar 757.1 mi
13h 21m$139–200Bus
- Take the bus from Knoxville to Memphis - Summer Avebus Nyc
- Take the bus from Memphis Bus Station to Lake Charlesbus FlixBus N2211
22h 33m$245–366Fly to Lafayette Regional Airport, train
- Fly from Mcghee Tyson Airport (TYS) to Lafayette Regional Airport (LFT)plane TYS - LFT
- Take the train from Lafayette Amtrak Station to Lake Charles Stationtrain
6h 34m$192–680
Mcghee Tyson Airport (TYS) to Lake Charles Regional Airport (LCH) flights
Questions & Answers
The cheapest way to get from Knoxville to Lake Charles is to drive which costs $130 - $200 and takes 13h 21m.
The fastest way to get from Knoxville to Lake Charles is to fly which takes 5h 24m and costs $180 - $750.
No, there is no direct bus from Knoxville to Lake Charles. However, there are services departing from Knoxville and arriving at Lake Charles via SUMMER AVENUE at WHITE STATION ROAD, William Hudson Transit Center and Memphis Bus Station. The journey, including transfers, takes approximately 22h 33m.
The distance between Knoxville and Lake Charles is 686 miles. The road distance is 761.5 miles.
The best way to get from Knoxville to Lake Charles without a car is to bus which takes 22h 33m and costs $240 - $370.
It takes approximately 5h 24m to get from Knoxville to Lake Charles, including transfers.
Knoxville to Lake Charles bus services, operated by Wanda Coach, depart from Knoxville station.
The best way to get from Knoxville to Lake Charles is to fly which takes 5h 24m and costs $180 - $750. Alternatively, you can bus, which costs $240 - $370 and takes 22h 33m.
Knoxville to Lake Charles bus services, operated by Wanda Coach, arrive at Memphis - Summer Ave station.
Lake Charles is 1h behind Knoxville. It is currently 6:19 AM in Knoxville and 5:19 AM in Lake Charles.
What companies run services between Knoxville, TN, USA and Lake Charles, LA, USA?
American Airlines and United Airlines fly from Mcghee Tyson Airport (TYS) to Lake Charles Regional Airport (LCH) 5 times a day. Alternatively, you can take a vehicle from Knoxville to Lake Charles via Knoxville, Memphis - Summer Ave, SUMMER AVENUE at WHITE STATION ROAD, William Hudson Transit Center, AIRWAYS BOULEVARD at BROOKS ROAD, and Memphis Bus Station in around 22h 33m.
- Website
- aa.com
Flights from Mcghee Tyson Airport to Lake Charles Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $140–700
Flights from Mcghee Tyson Airport to Lafayette Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 9m
- When
- Every day
- Estimated price
- $150–700
Flights from Mcghee Tyson Airport to Lafayette Regional Airport via Charlotte
- Ave. Duration
- 6h 29m
- When
- Every day
- Estimated price
- $130–650
- Website
- united.com
Flights from Mcghee Tyson Airport to Lake Charles Regional Airport via Houston
- Ave. Duration
- 7h 2m
- When
- Every day
- Estimated price
- $120–650
Flights from Mcghee Tyson Airport to Lafayette Regional Airport via Houston
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $130–650
- Website
- delta.com
Flights from Mcghee Tyson Airport to Lafayette Regional Airport via Atlanta
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $100–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Lafayette Amtrak Station to Lake Charles Station
- Ave. Duration
- 1h 31m
- Frequency
- 3 times a week
- Estimated price
- $24–50
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 646-630-7186
- [email protected]
- Website
- wandacoach.com
Bus from Knoxville to Memphis - Summer Ave
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $55–80
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $55–80
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Memphis Bus Station to Lake Charles
- Ave. Duration
- 11h 30m
- Frequency
- 5 times a week
- Estimated price
- $100–180
- Schedules at
- flixbus.com
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More Questions & Answers
Yes, the driving distance between Knoxville to Lake Charles is 762 miles. It takes approximately 13h 21m to drive from Knoxville to Lake Charles.
There are 131+ hotels available in Lake Charles.






