There are 5 ways to get from Knoxville to Lakeland by plane, car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Orlando Sanford, drive
best- Fly from Mcghee Tyson Airport (TYS) to Orlando Sanford (SFB)plane TYS - SFB
- Drive from Orlando-Sanford-Airport-SFB to Lakelandcar
3h 24m$160–587Drive 646.1 mi
cheapest- Drive from Knoxville to Lakelandcar 646.1 mi
11h 13m$118–171Bus, train
- Take the bus from Knoxville, TN to New York, NYbus Ny
- Take the train from Ny Moynihan Train Hall At Penn Station to Kissimmee Amtrak Stationtrain
- Take the train from Kissimmee Amtrak Station to Lakeland Amtrak Stationtrain
38h 40m$523–942Bus, train via Jacksonville
- Take the bus from Knoxville, TN to New York, NYbus Ny
- Take the bus from New York City Chinatown to Jacksonvillebus
- Take the train from Jacksonville to Lakeland Amtrak Stationtrain
42h$324–537Fly to Orlando, train
- Fly from Mcghee Tyson Airport (TYS) to Orlando (MCO)plane TYS - MCO
- Take the train from Kissimmee Amtrak Station to Lakeland Amtrak Stationtrain
5h 20m$164–602
Mcghee Tyson Airport (TYS) to Orlando Sanford (SFB) flights
Questions & Answers
The cheapest way to get from Knoxville to Lakeland is to drive which costs $110 - $170 and takes 11h 13m.
The fastest way to get from Knoxville to Lakeland is to fly and drive which takes 3h 24m and costs $160 - $600.
The distance between Knoxville and Lakeland is 602 miles. The road distance is 649.9 miles.
The best way to get from Knoxville to Lakeland without a car is to bus and train which takes 38h 40m and costs $500 - $950.
It takes approximately 3h 24m to get from Knoxville to Lakeland, including transfers.
Yes, the driving distance between Knoxville to Lakeland is 650 miles. It takes approximately 11h 13m to drive from Knoxville to Lakeland.
There are 280+ hotels available in Lakeland.
What companies run services between Knoxville, TN, USA and Lakeland, FL, USA?
There is no direct connection from Knoxville to Lakeland. However, you can take the taxi to Mcghee Tyson Airport (TYS) airport, fly to Orlando Sanford (SFB), then drive to Lakeland. Alternatively, you can take a vehicle from Knoxville to Lakeland Amtrak Station via Knoxville, TN, New York, NY, East Broadway, 34 St-Herald Sq, Ny Moynihan Train Hall At Penn Station, and Kissimmee Amtrak Station in around 38h 40m.
- Website
- allegiantair.com
Flights from Mcghee Tyson Airport to Orlando Sanford
- Ave. Duration
- 1h 36m
- When
- Thursday, Friday, Wednesday, Sunday, Monday, and Saturday
- Estimated price
- $90–500
Flights from Mcghee Tyson Airport to Orlando
- Ave. Duration
- 1h 40m
- When
- Friday and Monday
- Estimated price
- $90–500
- Website
- southwest.com
Flights from Mcghee Tyson Airport to Orlando
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $90–500
Flights from Mcghee Tyson Airport to Orlando via Nashville
- Ave. Duration
- 4h 2m
- When
- Tuesday to Friday
- Estimated price
- $110–600
- Website
- delta.com
Flights from Mcghee Tyson Airport to Orlando via Atlanta
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $90–550
- Website
- aa.com
Flights from Mcghee Tyson Airport to Orlando via Charlotte
- Ave. Duration
- 4h 8m
- When
- Sunday
- Estimated price
- $100–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Ny Moynihan Train Hall At Penn Station to Kissimmee Amtrak Station
- Ave. Duration
- 23h 8m
- Frequency
- Once daily
- Estimated price
- $370–750
- Website
- https://www.amtrak.com/home.html
Train from Kissimmee Amtrak Station to Lakeland Amtrak Station
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Estimated price
- $13–29
- Website
- https://www.amtrak.com/home.html
Train from Jacksonville to Lakeland Amtrak Station
- Ave. Duration
- 4h 40m
- Frequency
- Once daily
- Estimated price
- $65–140
- Website
- https://www.amtrak.com/home.html
Train from Kissimmee Amtrak Station to Lakeland Amtrak Station
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Estimated price
- $13–29
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 615-939-8887
- [email protected]
- Website
- nytnbus.com
Bus from Knoxville, TN to New York, NY
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- https://www.nytnbus.com
- Adult One-way
- $95–110
Bus from Knoxville, TN to New York, NY
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- https://www.nytnbus.com
- Adult One-way
- $95–110
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from New York City Chinatown to Jacksonville
- Ave. Duration
- 19h
- Frequency
- 5 times a week
- Estimated price
- $160–280
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide




