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How to get fromKnoxville to Las Vegasby plane, bus, train, or car

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There are 6 ways to get from Knoxville to Las Vegas by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mcghee Tyson Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Harry Reid International Airport (LAS)plane plane TYS - LAS
    4h 37m
    $261–921

  2. Drive to Asheville Regional Airport, fly

    cheapest
    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Harry Reid International Airport (LAS)plane plane AVL - LAS
    6h 43m
    $166–636

  3. Bus

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Tornado Bus Co - West Memphisbus bus
    3. Take the bus from Tornado Bus Co - West Memphis to Dallas Jeffersonbus bus
    4. Take the bus from Dallas to El Pasobus bus
    5. Take the bus from El Paso to Las Vegasbus bus
    43h 50m
    $474–900

  4. Bus, train via Kansas City

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Kansas Citytrain train
    4. Take the train from Kansas City to Kingman Stationtrain train
    5. Take the bus from Kingman, AZ to Las Vegasbus bus
    2d 2h
    $789–1,515

  5. Drive 1,963 mi

    1. Drive from Knoxville to Las Vegascar car 1,963 mi
    30h 38m
    $359–518

  6. Bus, train

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus bus
    3. Take the train from Indianapolis to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Kingman Stationtrain train
    5. Take the bus from Kingman Station to South Strip Transit Terminalbus bus
    2d 12h
    $940–1,896

Mcghee Tyson Airport (TYS) to Harry Reid International Airport (LAS) flights

Calendar34Weekly Planes
Duration6h 36mAverage Duration
Ticket$208Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Las Vegas.ExpandLaunch map view
  • Distance: 1,750.6 mi
  • Duration: 4h 37m

What companies run services between Knoxville, TN, USA and Las Vegas, NV, USA?

Allegiant Air, Southwest Airlines, and United Airlines fly from Mcghee Tyson Airport (TYS) to Harry Reid International Airport (LAS) 5 times a day. Alternatively, you can take a vehicle from Knoxville to Las Vegas via Knoxville, Jackson, El Mezcal Grocery - Jackson, TN, Tornado Bus Co - West Memphis, Dallas Jefferson, Dallas, and El Paso in around 43h 50m.

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