Rome2Rio

How to get fromKnoxville to Lewisburgby plane, bus, train, car, or bus (Flixbus)

Find Transport to Lewisburg

See all options

There are 5 ways to get from Knoxville to Lewisburg by plane, bus, train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Harrisburg International Airport, bus

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Harrisburg International Airport (MDT)plane plane TYS - MDT
    2. Take the bus from Harrisburg, Pa to Lewisburgbus bus
    7h 36m
    $161–609

  2. Drive 586.1 mi

    cheapest
    1. Drive from Knoxville to Lewisburgcar car 586.1 mi
    10h 7m
    $107–155

  3. Bus, train

    1. Take the bus from Knoxville, TN to New York, NYbus bus Ny
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Harrisburgtrain train
    3. Take the bus from Harrisburg, Pa to Lewisburgbus bus 29
    19h 35m
    $213–333

  4. Fly to Philadelphia International Airport, train, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Philadelphia International Airport (PHL)plane plane TYS - PHL
    2. Take the train from 30th Street Station to Harrisburgtrain train
    3. Take the bus from Harrisburg, Pa to Lewisburgbus bus
    8h 13m
    $228–875

  5. Bus

    1. Take the bus from Knoxville, TN to New York, NYbus bus Ny
    2. Take the bus from New York City Chinatown to Allentownbus bus
    3. Take the bus from Allentown to Lewisburgbus bus
    23h 14m
    $153–219

Mcghee Tyson Airport (TYS) to Harrisburg International Airport (MDT) flights

Calendar117Weekly Planes
Duration4h 47mAverage Duration
Ticket$87Cheapest Price
See schedules

Questions & Answers

Map of how to get from Knoxville to Lewisburg.ExpandLaunch map view
  • Distance: 586.6 mi
  • Duration: 7h 36m

What companies run services between Knoxville, TN, USA and Lewisburg, PA, USA?

You can take a bus from Knoxville Station Bay H to Lewisburg via Fountain City Superstop, Walmart, Knoxville, TN, New York City Chinatown, and Allentown in around 23h 14m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides