There are 3 ways to get from Knoxville to Lexington by car or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive 168.1 mi
best- Drive from Knoxville to Lexingtoncar 168.1 mi
2h 54m$31–45Fly to Louisville International Airport, drive
- Fly from Mcghee Tyson Airport (TYS) to Louisville International Airport (SDF)plane TYS - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
4h 32m$166–688Fly to Blue Grass Airport
- Fly from Mcghee Tyson Airport (TYS) to Blue Grass Airport (LEX)plane TYS - LEX
6h 18m$229–1,069
Mcghee Tyson Airport (TYS) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Knoxville to Lexington is to drive which costs $30 - $45 and takes 2h 54m.
The fastest way to get from Knoxville to Lexington is to drive which takes 2h 54m and costs $30 - $45.
The distance between Knoxville and Lexington is 169 miles. The road distance is 169.1 miles.
It takes approximately 2h 54m to drive 169.1 miles from Knoxville to Lexington.
Yes, the driving distance between Knoxville to Lexington is 169 miles. It takes approximately 2h 54m to drive from Knoxville to Lexington.
There are 156+ hotels available in Lexington.
What companies run services between Knoxville, TN, USA and Lexington, KY, USA?
Delta, American Airlines, and United Airlines fly from Mcghee Tyson Airport (TYS) to Blue Grass Airport (LEX) hourly.
- Website
- delta.com
Flights from Mcghee Tyson Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $120–700
Flights from Mcghee Tyson Airport to Louisville International Airport via Detroit
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $150–800
Flights from Mcghee Tyson Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $170–1,000
Flights from Mcghee Tyson Airport to Blue Grass Airport via Detroit
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $230–1,200
- Website
- aa.com
Flights from Mcghee Tyson Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 4h 54m
- When
- Every day
- Estimated price
- $120–700
Flights from Mcghee Tyson Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $170–1,000
Flights from Mcghee Tyson Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $240–1,200
- Website
- united.com
Flights from Mcghee Tyson Airport to Louisville International Airport via Washington Dulles
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $170–850
Flights from Mcghee Tyson Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 24m
- When
- Every day
- Estimated price
- $240–1,200
- Website
- southwest.com
Flights from Mcghee Tyson Airport to Louisville International Airport via Nashville
- Ave. Duration
- 3h 41m
- When
- Monday to Saturday
- Estimated price
- $95–600
Flights from Mcghee Tyson Airport to Louisville International Airport via Baltimore
- Ave. Duration
- 4h 20m
- When
- Sunday
- Estimated price
- $180–900
- Website
- allegiantair.com
Flights from Mcghee Tyson Airport to Louisville International Airport via Valparaiso
- Ave. Duration
- 3h 55m
- When
- Sunday and Thursday
- Estimated price
- $180–900
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