There are 5 ways to get from Knoxville to Lexington by plane, car, shuttle, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Piedmont Triad International Airport
best- Fly from Mcghee Tyson Airport (TYS) to Piedmont Triad International Airport (GSO)plane TYS - GSO
6h 25m$188–844Drive 248.9 mi
cheapest- Drive from Knoxville to Lexingtoncar 248.9 mi
4h 46m$46–66Drive, shuttle, bus
- Drive from Chilhowee at Holston to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Asheville Airport
- Take the bus from Asheville, NC to Winston Salem(Trans Center)bus
12h 7m$382–425Fly to Charlotte Douglas International Airport, train
- Fly from Mcghee Tyson Airport (TYS) to Charlotte Douglas International Airport (CLT)plane TYS - CLT
- Take the train from Charlotte Amtrak Station to High Pointtrain
6h 31m$166–727Drive, shuttle, bus via Charlotte Airport (CLT)
- Drive from Knoxville to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Boone
- Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
12h 12m$365–442
Mcghee Tyson Airport (TYS) to Piedmont Triad International Airport (GSO) flights
Questions & Answers
The cheapest way to get from Knoxville to Lexington is to drive which costs $45 - $70 and takes 4h 46m.
The fastest way to get from Knoxville to Lexington is to drive which takes 4h 46m and costs $45 - $70.
The distance between Knoxville and Lexington is 276 miles. The road distance is 250.4 miles.
It takes approximately 6h 25m to get from Knoxville to Lexington, including transfers.
Yes, the driving distance between Knoxville to Lexington is 250 miles. It takes approximately 4h 46m to drive from Knoxville to Lexington.
There are 39+ hotels available in Lexington.
What companies run services between Knoxville, TN, USA and Lexington, NC, USA?
American Airlines, Delta, and United Airlines fly from Mcghee Tyson Airport (TYS) to Piedmont Triad International Airport (GSO) hourly.
- Website
- aa.com
Flights from Mcghee Tyson Airport to Piedmont Triad International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $110–750
Flights from Mcghee Tyson Airport to Piedmont Triad International Airport via Philadelphia
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Mcghee Tyson Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $80–600
- Website
- delta.com
Flights from Mcghee Tyson Airport to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $140–850
Flights from Mcghee Tyson Airport to Piedmont Triad International Airport via Detroit
- Ave. Duration
- 6h 2m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $210–1,100
Flights from Mcghee Tyson Airport to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 3h 39m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–700
- Website
- united.com
Flights from Mcghee Tyson Airport to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $170–950
- Website
- southwest.com
Flights from Mcghee Tyson Airport to Charlotte Douglas International Airport via Nashville
- Ave. Duration
- 3h 30m
- When
- Sunday
- Estimated price
- $120–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Charlotte Amtrak Station to High Point
- Ave. Duration
- 1h 14m
- Frequency
- 5 times a day
- Estimated price
- $23–50
- Website
- Amtrak
- Phone
- +1-423-725-5988
- Website
- Black Bear Resort Shuttle
Shuttle from Hot Springs to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- Black Bear Resort Shuttle
Shuttle from Black Bear Resort to Asheville Airport
- Ave. Duration
- 2h 30m
- Frequency
- On demand
- Estimated price
- $168
- Website
- Black Bear Resort Shuttle
Shuttle from Hot Springs to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- Black Bear Resort Shuttle
Shuttle from Black Bear Resort to Boone
- Ave. Duration
- 1h
- Frequency
- On demand
- Estimated price
- $86
- Website
- Black Bear Resort Shuttle
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Asheville, NC to Winston Salem(Trans Center)
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $21–45
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $11–22
- Website
- Greyhound
- Phone
- +1 828-327-2340
- [email protected]
- Website
- Hickory Hop
Bus from ASU Peacock Hall Boone to Charlotte Airport
- Ave. Duration
- 2h 30m
- Frequency
- Every 4 hours
- Estimated price
- $90–110
- Schedules at
- Hickory Hop
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $7–40
- Website
- Barons Bus
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