There are 3 ways to get from Knoxville to Lexington by plane, car, shuttle, taxi, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Mcghee Tyson Airport (TYS) to Columbia (CAE)plane TYS - CAE
3h 35m$245–1,202Drive 259.3 mi
cheapest- Drive from Knoxville to Lexingtoncar 259.3 mi
4h 34m$48–69Drive, shuttle, taxi, bus
- Drive from Chilhowee at Holston to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take the taxi from Black Bear Resort to ASU Peacock Hall Boonetaxi
- Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Columbia, SCbus Nyc
13h 11m$459–564
Mcghee Tyson Airport (TYS) to Columbia (CAE) flights
Questions & Answers
The cheapest way to get from Knoxville to Lexington is to drive which costs $45 - $70 and takes 4h 34m.
The fastest way to get from Knoxville to Lexington is to fly which takes 3h 35m and costs $240 - $1,200.
The distance between Knoxville and Lexington is 229 miles. The road distance is 260.8 miles.
It takes approximately 3h 35m to get from Knoxville to Lexington, including transfers.
Yes, the driving distance between Knoxville to Lexington is 261 miles. It takes approximately 4h 34m to drive from Knoxville to Lexington.
There are 312+ hotels available in Lexington.
What companies run services between Knoxville, TN, USA and Lexington, SC, USA?
Delta, American Airlines, and United Airlines fly from Mcghee Tyson Airport (TYS) to Columbia (CAE) hourly.
- Website
- aa.com
Flights from Mcghee Tyson Airport to Columbia via Charlotte
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $160–1,100
Flights from Mcghee Tyson Airport to Columbia via Reagan Washington
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $310–1,600
Flights from Mcghee Tyson Airport to Columbia via Philadelphia
- Ave. Duration
- 5h 50m
- When
- Every day
- Estimated price
- $370–1,700
- Website
- delta.com
Flights from Mcghee Tyson Airport to Columbia via Atlanta
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $180–1,200
Flights from Mcghee Tyson Airport to Columbia via New York La Guardia
- Ave. Duration
- 7h 2m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $410–1,900
- Website
- united.com
Flights from Mcghee Tyson Airport to Columbia via Washington Dulles
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $300–1,500
Flights from Mcghee Tyson Airport to Columbia via Chicago O'Hare
- Ave. Duration
- 6h 23m
- When
- Every day
- Estimated price
- $380–1,800
- Phone
- +1-423-725-5988
- Website
- Black Bear Resort Shuttle
Shuttle from Hot Springs to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- Black Bear Resort Shuttle
- Phone
- +1 828-327-2340
- [email protected]
- Website
- Hickory Hop
Bus from ASU Peacock Hall Boone to Charlotte Airport
- Ave. Duration
- 2h 30m
- Frequency
- Every 4 hours
- Estimated price
- $90–110
- Schedules at
- Hickory Hop
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- $11–23
- Website
- Greyhound
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from Camden to Columbia, SC
- Ave. Duration
- 42 min
- Frequency
- Once daily
- Estimated price
- $28–40
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $28–40
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