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How to get fromKnoxville to Little Riverby plane, car, shuttle, bus, taxi, or train

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There are 6 ways to get from Knoxville to Little River by plane, car, shuttle, bus, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Myrtle Beach

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Myrtle Beach (MYR)plane plane TYS - MYR
    4h 13m
    $172–452

  2. Drive  417.7 mi

    cheapest
    1. Drive from Knoxville to Little Rivercar car 417.7 mi
    7h 32m
    $74–107

  3. Drive, shuttle, bus, taxi

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    4. Take the bus from Boone to Winston-Salembus bus
    5. Take the bus from Winston-Salem to Fayettevillebus bus
    6. Take the bus from Fayetteville Bus Station to Whiteville Columbus County Transitbus bus
    7. Take the taxi from Whiteville Columbus County Transit to Little Rivertaxi taxi
    15h 41m
    $395–466

  4. Fly to Wilmington International Airport, drive

    1. Fly from Mcghee Tyson Airport (TYS) to Wilmington International Airport (ILM)plane plane TYS - ILM
    2. Drive from Wilmington International Airport (ILM) to Little Rivercar car
    4h 49m
    $131–521

  5. Drive, shuttle, bus, taxi via Charlotte

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    4. Take the bus from Boone to Charlottebus bus
    5. Take the bus from Charlotte Bus Station to Whiteville Columbus County Transitbus bus
    6. Take the taxi from Whiteville Columbus County Transit to Little Rivertaxi taxi
    16h 31m
    $397–470

  6. Drive, shuttle, taxi, bus, train

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Boonetaxi taxi
    4. Take the bus from Boone to Forsyth Hospitalbus bus
    5. Take the train from High Point to Selma Stationtrain train
    6. Take the train from Selma Station to Fayetteville Amtrak Stationtrain train
    7. Take the bus from Fayetteville Bus Station to Whiteville Columbus County Transitbus bus
    8. Take the taxi from Whiteville Columbus County Transit to Little Rivertaxi taxi
    17h 30m
    $497–650

Mcghee Tyson Airport (TYS) to Myrtle Beach (MYR) flights

Calendar47Weekly Planes
Duration4h 8mAverage Duration
Ticket$47Cheapest Price
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Comparing Your Travel Options

Map of how to get from Knoxville to Little River.ExpandLaunch map view
  • Distance: 358.9 mi
  • Duration: 4h 13m

What companies run services between Knoxville, TN, USA and Little River, SC, USA?

American Airlines, Delta, and Southwest Airlines fly from Mcghee Tyson Airport (TYS) to Myrtle Beach (MYR) every 4 hours.

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