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How to get fromKnoxville to Louisianaby plane, bus, train, or car

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There are 5 ways to get from Knoxville to Louisiana by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Louis Armstrong New Orleans International Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Louis Armstrong New Orleans International Airport (MSY)plane plane TYS - MSY
    3h 47m
    $177–717

  2. Drive 598.4 mi

    cheapest
    1. Drive from Knoxville to New Orleanscar car 598.4 mi
    9h 48m
    $110–158

  3. Bus, train

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to Jacksonbus bus
    3. Take the train from Jackson to New Orleans Union Passenger Terminaltrain train
    17h 1m
    $264–425

  4. Fly to Lafayette Regional Airport

    1. Fly from Mcghee Tyson Airport (TYS) to Lafayette Regional Airport (LFT)plane plane TYS - LFT
    4h 4m
    $168–630

  5. Fly to Shreveport

    1. Fly from Mcghee Tyson Airport (TYS) to Shreveport (SHV)plane plane TYS - SHV
    5h 51m
    $167–667

Mcghee Tyson Airport (TYS) to Louis Armstrong New Orleans International Airport (MSY) flights

Calendar48Weekly Planes
Duration4h 31mAverage Duration
Ticket$120Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Louisiana.ExpandLaunch map view
  • Distance: 554.2 mi
  • Duration: 3h 47m

What companies run services between Knoxville, TN, USA and Louisiana, USA?

Southwest Airlines, Delta, and American Airlines fly from Mcghee Tyson Airport (TYS) to Louis Armstrong New Orleans International Airport (MSY) every 4 hours.

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