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How to get fromKnoxville to Lowellby plane, bus, train, car, shuttle, or taxi

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There are 6 ways to get from Knoxville to Lowell by plane, bus, train, car, shuttle, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mcghee Tyson Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Boston Logan Airport (BOS)plane plane TYS - BOS
    4h 33m
    $178–634

  2. Drive to Asheville Regional Airport, fly

    cheapest
    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Boston Logan Airport (BOS)plane plane AVL - BOS
    6h 21m
    $108–429

  3. Bus, train

    1. Take the bus from Knoxville, TN to New York, NYbus bus Ny
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train
    3. Take the train from North Station to Lowelltrain train
    18h 31m
    $222–337

  4. Drive, shuttle, taxi, bus, train

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Bristol Exit 5 Park & Ride Lottaxi taxi
    4. Take the bus from Park and Ride Lot at I-81 Exit 5 to Route 460 Park and Ridebus bus
    5. Take the bus from Exit 118 - Park and Ride to Roanoke Campbell Courtbus bus Swb
    6. Take the train from Roanoke to Bostontrain train
    7. Take the train from North Station to Lowelltrain train
    29h 3m
    $492–788

  5. Drive 912.4 mi

    1. Drive from Knoxville to Lowellcar car 912.4 mi
    15h 58m
    $167–241

  6. Drive, shuttle, taxi, bus, train via Washington

    1. Drive from Chilhowee at Holston to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Bristol Exit 5 Park & Ride Lottaxi taxi
    4. Take the bus from Park and Ride Lot at I-81 Exit 5 to DC Union Stationbus bus
    5. Take the bus from Washington Union Station to Bostonbus bus
    6. Take the train from North Station to Lowelltrain train
    26h 7m
    $372–520

Mcghee Tyson Airport (TYS) to Boston Logan Airport (BOS) flights

Calendar65Weekly Planes
Duration4h 28mAverage Duration
Ticket$113Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Lowell.ExpandLaunch map view
  • Distance: 868.9 mi
  • Duration: 4h 33m

What companies run services between Knoxville, TN, USA and Lowell, MA, USA?

Allegiant Air, Southwest Airlines, and three other airlines fly from Mcghee Tyson Airport (TYS) to Boston Logan Airport (BOS) every 3 hours.

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