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How to get fromKnoxville to Manhattanby plane, bus, car, or train

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There are 8 ways to get from Knoxville to Manhattan by plane, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mcghee Tyson Airport to Laguardia Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Laguardia Airport (LGA)plane plane TYS - LGA
    3h 1m
    $180–770

  2. Drive to Asheville Regional Airport, fly to Newark Liberty International Airport

    cheapest
    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Newark Liberty International Airport (EWR)plane plane AVL - EWR
    4h 46m
    $98–380

  3. Bus

    1. Take the bus from Knoxville, TN to New York, NYbus bus Ny
    12h 42m
    $140–163

  4. Drive 706.7 mi

    1. Drive from Knoxville to Manhattancar car 706.7 mi
    12h 7m
    $129–187

  5. Fly Mcghee Tyson Airport to Newark Liberty International Airport

    1. Fly from Mcghee Tyson Airport (TYS) to Newark Liberty International Airport (EWR)plane plane TYS - EWR
    2h 58m
    $148–495

  6. Drive to Chattanooga Metropolitan Airport, fly to Laguardia Airport

    1. Drive from Knoxville to Chattanooga Metropolitan Airport (CHA)car car
    2. Fly from Chattanooga Metropolitan Airport (CHA) to Laguardia Airport (LGA)plane plane CHA - LGA
    4h 42m
    $122–630

  7. Fly Mcghee Tyson Airport to Philadelphia International Airport, train

    1. Fly from Mcghee Tyson Airport (TYS) to Philadelphia International Airport (PHL)plane plane TYS - PHL
    2. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4h 27m
    $175–1,220

  8. Drive to Asheville Regional Airport, fly to Laguardia Airport

    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Laguardia Airport (LGA)plane plane AVL - LGA
    4h 53m
    $120–585

Mcghee Tyson Airport (TYS) to Laguardia Airport (LGA) flights

Calendar81Weekly Planes
Duration3h 29mAverage Duration
Ticket$122Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Manhattan.ExpandLaunch map view
  • Distance: 666.7 mi
  • Duration: 3h 1m

What companies run services between Knoxville, TN, USA and Manhattan, NY, USA?

American Airlines, Delta, and two other airlines fly from Mcghee Tyson Airport (TYS) to Laguardia Airport (LGA) every 2 hours. Alternatively, NYTN Bus operates a bus from Knoxville, TN to New York, NY once daily. Tickets cost $95–110 and the journey takes 12h.

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