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How to get fromKnoxville to Manningby plane, taxi, car, shuttle, or bus

Find Transport to Manning

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There are 5 ways to get from Knoxville to Manning by plane, taxi, car, shuttle, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Regional Airport, taxi

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Florence Regional Airport (FLO)plane plane TYS - FLO
    2. Take the taxi from Florence Regional Airport (FLO) to Manningtaxi taxi
    4h 47m
    $272–677

  2. Drive 324.4 mi

    cheapest
    1. Drive from Knoxville to Manningcar car 324.4 mi
    6h 1m
    $60–86

  3. Drive, shuttle, bus

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    4. Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus bus
    5. Take the bus from Charlotte Bus Station to Sumter Bus Stopbus bus
    12h 57m
    $405–467

  4. Fly to Columbia, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Columbia (CAE)plane plane TYS - CAE
    2. Take the bus from Laurel Sumter East to James E Clyburn Intermodal Transportation Centerbus bus
    7h 42m
    $281–1,246

  5. Drive, shuttle, taxi, bus

    1. Drive from Chilhowee at Holston to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to ASU Peacock Hall Boonetaxi taxi
    4. Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus bus
    5. Take the bus from Charlotte Bus Station to Sumter Bus Stopbus bus
    13h 19m
    $440–532

Mcghee Tyson Airport (TYS) to Florence Regional Airport (FLO) flights

Calendar14Weekly Planes
Duration4h 21mAverage Duration
Ticket$67Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Manning.ExpandLaunch map view
  • Distance: 327 mi
  • Duration: 4h 47m

What companies run services between Knoxville, TN, USA and Manning, SC, USA?

There is no direct connection from Knoxville to Manning. However, you can take the taxi to Mcghee Tyson Airport (TYS) airport, fly to Florence Regional Airport (FLO), then take the taxi to Manning. Alternatively, you can take a vehicle from Knoxville to Manning via Hot Springs, Black Bear Resort, Boone, ASU Peacock Hall Boone, Charlotte Airport, Charlotte Douglas Airport, Transit Center- Bay V, Transit Center- Bay E, 4th St & Graham St, Charlotte Bus Station, and Sumter Bus Stop in around 12h 57m.

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