There are 5 ways to get from Knoxville to Mebane by plane, bus, car, shuttle, taxi, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Raleigh-Durham International Airport, bus
best- Fly from Mcghee Tyson Airport (TYS) to Raleigh-Durham International Airport (RDU)plane TYS - RDU
- Take the bus from Willard St at Durham Station to E Washington St at S 5th Stbus
6h 57m$131–516Drive 300.6 mi
cheapest- Drive from Knoxville to Mebanecar 300.6 mi
5h 46m$55–80Drive, shuttle, bus
- Drive from Knoxville to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Boone
- Take the bus from Boone to Winston-Salembus
- Take the bus from Winston-Salem to Greensborobus
- Take the bus from Greensboro Depot to Mebane Cone Health Park & Ridebus 4
12h 33m$262–278Fly to Piedmont Triad International Airport, bus
- Fly from Mcghee Tyson Airport (TYS) to Piedmont Triad International Airport (GSO)plane TYS - GSO
- Take the bus from Coble Transportation Center to Mebane Cone Health Park & Ridebus
7h 11m$179–793Drive, shuttle, taxi, bus, train
- Drive from Knoxville to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take the taxi from Black Bear Resort to Boonetaxi
- Take the bus from Boone to Forsyth Hospitalbus
- Take the train from High Point to Durham Amtrak Stationtrain
- Take the bus from Willard St at Durham Station to E Washington St at S 5th Stbus Odx
12h 41m$306–370
Mcghee Tyson Airport (TYS) to Raleigh-Durham International Airport (RDU) flights
Comparing Your Travel Options
The cheapest way to get from Knoxville to Mebane is to drive which costs $55 - $80 and takes 5h 46m.
The fastest way to get from Knoxville to Mebane is to drive which takes 5h 46m and costs $55 - $80.
The distance between Knoxville and Mebane is 350 miles. The road distance is 302.4 miles.
It takes approximately 6h 57m to get from Knoxville to Mebane, including transfers.
Yes, the driving distance between Knoxville to Mebane is 302 miles. It takes approximately 5h 46m to drive from Knoxville to Mebane.
There are 63+ hotels available in Mebane.
What companies run services between Knoxville, TN, USA and Mebane, NC, USA?
There is no direct connection from Knoxville to Mebane. However, you can take the taxi to Mcghee Tyson Airport (TYS) airport, fly to Raleigh-Durham International Airport (RDU), walk to RDU Airport at Terminal 2, take the line 100 bus to Regional Transit Center, take the line 700 bus to Duke St at Jackson St, walk to Willard St at Durham Station, then take the bus to E Washington St at S 5th St. Alternatively, you can take a vehicle from Knoxville to E Washington St at S 5th St via Hot Springs, Black Bear Resort, Boone, Boone, Winston-Salem, Greensboro, Greensboro Depot, and Mebane Cone Health Park-and-Ride in around 12h 33m.
- Website
- aa.com
Flights from Mcghee Tyson Airport to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $65–440
Flights from Mcghee Tyson Airport to Raleigh-Durham International Airport via Reagan Washington
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $100–550
Flights from Mcghee Tyson Airport to Piedmont Triad International Airport via Charlotte
- Ave. Duration
- 3h 39m
- When
- Every day
- Estimated price
- $100–700
Flights from Mcghee Tyson Airport to Piedmont Triad International Airport via Philadelphia
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $200–1,000
Flights from Mcghee Tyson Airport to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 6h 20m
- When
- Every day
- Estimated price
- $160–900
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from High Point to Durham Amtrak Station
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $18–40
- Website
- Amtrak
- Phone
- +1 919 485 7433
- [email protected]
- Website
- gotriangle.org
Bus from Willard St at Durham Station to E Washington St at S 5th St
- Ave. Duration
- 51 min
- Frequency
- Twice daily
- Estimated price
- $3
- Website
- gotriangle.org
Bus from Willard St at Durham Station to E Washington St at S 5th St
- Ave. Duration
- 51 min
- Frequency
- Twice daily
- Estimated price
- $3
- Website
- gotriangle.org
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