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How to get fromKnoxville to Mebaneby plane, bus, car, shuttle, taxi, or train

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There are 5 ways to get from Knoxville to Mebane by plane, bus, car, shuttle, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Raleigh-Durham International Airport, bus

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Raleigh-Durham International Airport (RDU)plane plane TYS - RDU
    2. Take the bus from Willard St at Durham Station to E Washington St at S 5th Stbus bus
    6h 57m
    $131–516

  2. Drive  300.6 mi

    cheapest
    1. Drive from Knoxville to Mebanecar car 300.6 mi
    5h 46m
    $55–80

  3. Drive, shuttle, bus

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    4. Take the bus from Boone to Winston-Salembus bus
    5. Take the bus from Winston-Salem to Greensborobus bus
    6. Take the bus from Greensboro Depot to Mebane Cone Health Park & Ridebus bus 4
    12h 33m
    $262–278

  4. Fly to Piedmont Triad International Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Piedmont Triad International Airport (GSO)plane plane TYS - GSO
    2. Take the bus from Coble Transportation Center to Mebane Cone Health Park & Ridebus bus
    7h 11m
    $179–793

  5. Drive, shuttle, taxi, bus, train

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Boonetaxi taxi
    4. Take the bus from Boone to Forsyth Hospitalbus bus
    5. Take the train from High Point to Durham Amtrak Stationtrain train
    6. Take the bus from Willard St at Durham Station to E Washington St at S 5th Stbus bus Odx
    12h 41m
    $306–370

Mcghee Tyson Airport (TYS) to Raleigh-Durham International Airport (RDU) flights

Calendar143Weekly Planes
Duration3h 58mAverage Duration
Ticket$68Cheapest Price
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Comparing Your Travel Options

Map of how to get from Knoxville to Mebane.ExpandLaunch map view
  • Distance: 348 mi
  • Duration: 6h 57m

What companies run services between Knoxville, TN, USA and Mebane, NC, USA?

There is no direct connection from Knoxville to Mebane. However, you can take the taxi to Mcghee Tyson Airport (TYS) airport, fly to Raleigh-Durham International Airport (RDU), walk to RDU Airport at Terminal 2, take the line 100 bus to Regional Transit Center, take the line 700 bus to Duke St at Jackson St, walk to Willard St at Durham Station, then take the bus to E Washington St at S 5th St. Alternatively, you can take a vehicle from Knoxville to E Washington St at S 5th St via Hot Springs, Black Bear Resort, Boone, Boone, Winston-Salem, Greensboro, Greensboro Depot, and Mebane Cone Health Park-and-Ride in around 12h 33m.

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