Rome2Rio

How to get fromKnoxville to Mebaneby plane, bus, car, or bus (Flixbus)

Find Transport to Mebane

See all options

There are 5 ways to get from Knoxville to Mebane by plane, bus, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Raleigh-Durham International Airport, bus

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Raleigh-Durham International Airport (RDU)plane plane TYS - RDU
    2. Take the bus from Willard St at Durham Station to E Washington St at S 5th Stbus bus
    6h 57m
    $141–556

  2. Drive 296.6 mi

    cheapest
    1. Drive from Knoxville to Mebanecar car 296.6 mi
    5h 55m
    $55–79

  3. Bus via Durham

    1. Take the bus from Knoxville, TN to New York, NYbus bus Ny
    2. Take the bus from New York, NY to Durhambus bus Nyc
    3. Take the bus from Willard St at Durham Station to E Washington St at S 5th Stbus bus Odx
    25h 32m
    $177–228

  4. Fly to Piedmont Triad International Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Piedmont Triad International Airport (GSO)plane plane TYS - GSO
    2. Take the bus from Coble Transportation Center to Mebane Cone Health Park & Ridebus bus
    7h 25m
    $179–793

  5. Bus

    1. Take the bus from Knoxville, TN to New York, NYbus bus Ny
    2. Take the bus from New York City Chinatown to Durhambus bus
    3. Take the bus from Willard St at Durham Station to E Washington St at S 5th Stbus bus Odx
    29h 30m
    $186–267

Mcghee Tyson Airport (TYS) to Raleigh-Durham International Airport (RDU) flights

Calendar114Weekly Planes
Duration4h 4mAverage Duration
Ticket$78Cheapest Price
See schedules

Questions & Answers

Map of how to get from Knoxville to Mebane.ExpandLaunch map view
  • Distance: 348 mi
  • Duration: 6h 57m

What companies run services between Knoxville, TN, USA and Mebane, NC, USA?

You can take a bus from Knoxville Station Bay H to E Washington St at S 5th St via Fountain City Superstop, Walmart, Knoxville, TN, New York, NY, Durham, North Pointe Dr at Woodmont Dr, Chapel Hill St at Duke St, and Willard St at Durham Station in around 25h 32m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides