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How to get fromKnoxville to Mesaby plane, bus, train, or car

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There are 4 ways to get from Knoxville to Mesa by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Phoenix (PHX)plane plane TYS - PHX
    5h 13m
    $179–619

  2. Bus

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Tornado Bus Co - West Memphisbus bus
    3. Take the bus from Tornado Bus Co - West Memphis to Tornado Bus Co - San Antoniobus bus
    4. Take the bus from San Antonio, TX - Tornado Bus Co to El Paso, TX - Tornado Bus Cobus bus
    5. Take the bus from El Paso to Phoenixbus bus
    40h 28m
    $479–717

  3. Bus, train

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to Jacksonbus bus
    3. Take the train from Jackson to New Orleans Union Passenger Terminaltrain train
    4. Take the train from New Orleans Union Passenger Terminal to Tucson Amtrak Stationtrain train
    5. Take the bus from Tucson Downtown to Tempebus bus
    2d 9h
    $1,128–1,778

  4. Drive  1,796.5 mi

    1. Drive from Knoxville to Mesacar car 1,796.5 mi
    28h 36m
    $307–444

Mcghee Tyson Airport (TYS) to Phoenix (PHX) flights

Calendar72Weekly Planes
Duration6h 8mAverage Duration
Ticket$120Cheapest Price
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Comparing Your Travel Options

Map of how to get from Knoxville to Mesa.ExpandLaunch map view
  • Distance: 1,620 mi
  • Duration: 5h 13m

What companies run services between Knoxville, TN, USA and Mesa, AZ, USA?

Allegiant Air, Southwest Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Phoenix (PHX) every 3 hours. Alternatively, you can take a vehicle from Knoxville to Center/Main St via Knoxville, Jackson, El Mezcal Grocery - Jackson, TN, Tornado Bus Co - West Memphis, San Antonio, TX - Tornado Bus Co, El Paso, TX - Tornado Bus Co, El Paso, Phoenix, and 24th St/Jefferson in around 40h 28m.

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