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How to get fromKnoxville to Mesaby plane, bus, train, taxi, or car

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There are 5 ways to get from Knoxville to Mesa by plane, bus, train, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Phoenix (PHX)plane plane TYS - PHX
    5h 16m
    $209–769

  2. Bus

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Tornado Bus Co - West Memphisbus bus
    3. Take the bus from Tornado Bus Co - West Memphis to Tornado Bus Co - San Antoniobus bus
    4. Take the bus from San Antonio, TX - Tornado Bus Co to El Paso, TX - Tornado Bus Cobus bus
    5. Take the bus from El Paso to Phoenixbus bus
    40h 31m
    $479–717

  3. Bus, train, taxi

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to Jacksonbus bus
    3. Take the train from Jackson to New Orleans Union Passenger Terminaltrain train
    4. Take the train from New Orleans Union Passenger Terminal to Maricopa Amtraktrain train
    5. Take the taxi from Maricopa Amtrak to Mesataxi taxi
    2d 8h
    $1,244–1,955

  4. Drive  1,796.5 mi

    1. Drive from Knoxville to Mesacar car 1,796.5 mi
    28h 36m
    $328–474

  5. Bus, train

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus bus
    3. Take the train from Indianapolis to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Flagstafftrain train
    5. Take the bus from Flagstaff Train Station to Tempebus bus
    2d 10h
    $1,275–2,028

Mcghee Tyson Airport (TYS) to Phoenix (PHX) flights

Calendar66Weekly Planes
Duration6h 12mAverage Duration
Ticket$156Cheapest Price
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Comparing Your Travel Options

Map of how to get from Knoxville to Mesa.ExpandLaunch map view
  • Distance: 1,620.5 mi
  • Duration: 5h 16m

What companies run services between Knoxville, TN, USA and Mesa, AZ, USA?

Allegiant Air, Southwest Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Phoenix (PHX) every 3 hours. Alternatively, you can take a vehicle from Knoxville to Mesa Dr/Main St via Knoxville, Jackson, El Mezcal Grocery - Jackson, TN, Tornado Bus Co - West Memphis, San Antonio, TX - Tornado Bus Co, El Paso, TX - Tornado Bus Co, El Paso, Phoenix, and 24th St/Jefferson in around 40h 31m.

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