Rome2Rio

How to get fromKnoxville to Milwaukeeby plane, bus, train, or car

Find Transport to Milwaukee

See all options

There are 5 ways to get from Knoxville to Milwaukee by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to General Mitchell International Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to General Mitchell International Airport (MKE)plane plane TYS - MKE
    4h 50m
    $190–770

  2. Drive 614.9 mi

    cheapest
    1. Drive from Knoxville to Milwaukeecar car 614.9 mi
    10h 55m
    $113–163

  3. Bus, train

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Central 5Th Ave - Bay 11 to Clarksville Exit 11 Park And Ridebus bus 94
    3. Take the bus from Clarksville Park & Ride to Carbondale Intermodal Stationbus bus
    4. Take the train from Carbondale to Chicago Union Stationtrain train
    5. Take the train from Chicago Union Station to Milwaukeetrain train
    18h 44m
    $286–484

  4. Fly to Chicago O'Hare International Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Chicago O'Hare International Airport (ORD)plane plane TYS - ORD
    2. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    4h 44m
    $141–486

  5. Bus

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Tornado Bus Co - West Memphisbus bus
    3. Take the bus from Tornado Bus Co - West Memphis to Water & Chicago - Circle Kbus bus
    21h
    $279–550

Mcghee Tyson Airport (TYS) to General Mitchell International Airport (MKE) flights

Calendar120Weekly Planes
Duration4h 55mAverage Duration
Ticket$129Cheapest Price
See schedules

Questions & Answers

Map of how to get from Knoxville to Milwaukee.ExpandLaunch map view
  • Distance: 554.9 mi
  • Duration: 4h 50m

What companies run services between Knoxville, TN, USA and Milwaukee, WI, USA?

Delta, United Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to General Mitchell International Airport (MKE) hourly. Alternatively, you can take a vehicle from Knoxville to Water & Chicago - Circle K via Knoxville, Jackson, El Mezcal Grocery - Jackson, TN, and Tornado Bus Co - West Memphis in around 21h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers