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How to get fromKnoxville to Minneapolis–Saint Paulby plane, bus, train, car, or bus (Greyhound, Flixbus)

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There are 6 ways to get from Knoxville to Minneapolis–Saint Paul by plane, bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mcghee Tyson Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Minneapolis–Saint Paul International Airport (MSP)plane plane TYS - MSP
    3h 37m
    $191–821

  2. Drive to Asheville Regional Airport, fly

    cheapest
    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Minneapolis–Saint Paul International Airport (MSP)plane plane AVL - MSP
    5h 32m
    $126–586

  3. Bus, train

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    24h 8m
    $325–581

  4. Drive 931.1 mi

    1. Drive from Knoxville to Minneapolis–Saint Paulcar car 931.1 mi
    15h 50m
    $170–246

  5. Bus

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Tornado Bus Co - West Memphisbus bus
    3. Take the bus from Tornado Bus Co - West Memphis to Water & Chicago - Circle Kbus bus
    4. Take the bus from Milwaukee Intermodal Station to Saint Paul Union Depotbus bus
    28h 22m
    $361–663

  6. Bus, train via Memphis

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Tornado Bus Co - West Memphisbus bus
    3. Take the bus from Tornado Bus Co - West Memphis to Water & Chicago - Circle Kbus bus
    4. Take the train from Milwaukee to St. Paul-Minneapolistrain train
    28h 39m
    $381–773

Mcghee Tyson Airport (TYS) to Minneapolis–Saint Paul International Airport (MSP) flights

Calendar87Weekly Planes
Duration4h 29mAverage Duration
Ticket$139Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Minneapolis–Saint Paul.ExpandLaunch map view
  • Distance: 815.1 mi
  • Duration: 3h 37m

What companies run services between Knoxville, TN, USA and Minneapolis–Saint Paul, MN, USA?

Delta, Southwest Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Minneapolis–Saint Paul International Airport (MSP) every 2 hours. Alternatively, you can take a vehicle from Knoxville to Marshall & Otis Station via Knoxville, Jackson, El Mezcal Grocery - Jackson, TN, Tornado Bus Co - West Memphis, Water & Chicago - Circle K, Milwaukee Intermodal Station, Saint Paul Union Depot, and Union Depot & Gate A1 in around 28h 22m.

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