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How to get fromKnoxville to Minnesotaby plane, bus, train, car, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Knoxville to Minnesota by plane, bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Minneapolis–Saint Paul International Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Minneapolis–Saint Paul International Airport (MSP)plane plane TYS - MSP
    3h 14m
    $179–719

  2. Fly to Rochester

    cheapest
    1. Fly from Mcghee Tyson Airport (TYS) to Rochester (RST)plane plane TYS - RST
    6h 17m
    $153–607

  3. Bus, train

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    24h 25m
    $310–551

  4. Drive 934.9 mi

    1. Drive from Knoxville to Minneapoliscar car 934.9 mi
    15h 53m
    $171–247

  5. Fly to Duluth International Airport

    1. Fly from Mcghee Tyson Airport (TYS) to Duluth International Airport (DLH)plane plane TYS - DLH
    6h 23m
    $158–619

  6. Bus, train via Memphis

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Tornado Bus Co - West Memphisbus bus
    3. Take the bus from Tornado Bus Co - West Memphis to Water & Chicago - Circle Kbus bus
    4. Take the train from Milwaukee to St. Paul-Minneapolistrain train
    28h 39m
    $379–573

  7. Bus

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Minneapolis Bus Stationbus bus
    28h 56m
    $336–486

Mcghee Tyson Airport (TYS) to Minneapolis–Saint Paul International Airport (MSP) flights

Calendar81Weekly Planes
Duration4h 27mAverage Duration
Ticket$125Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Minnesota.ExpandLaunch map view
  • Distance: 811.6 mi
  • Duration: 3h 14m

What companies run services between Knoxville, TN, USA and Minnesota, USA?

Delta, Southwest Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Minneapolis–Saint Paul International Airport (MSP) every 2 hours. Alternatively, you can take a vehicle from Knoxville to Minneapolis Bus Station via Knoxville, Jackson, El Mezcal Grocery - Jackson, TN, Indianapolis, Indianapolis Union Station, and Chicago Bus Station in around 28h 56m.

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