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How to get fromKnoxville to Mississaugaby plane, bus, train, bus (Flixbus), car, shuttle, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Knoxville to Mississauga by plane, bus, train, bus (Flixbus), car, shuttle, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Toronto Pearson International Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Toronto Pearson International Airport (YYZ)plane plane TYS - YYZ
    5h
    $204–750

  2. Bus, train

    1. Take the bus from Knoxville, TN to New York, NYbus bus Ny
    2. Take the train from New York Penn Station to Toronto Union Stationtrain train VIA Rail
    27h 37m
    $401–695

  3. Bus via Speedway

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus bus
    3. Take the bus from Indianapolis, IN to Detroit, MIbus bus
    4. Take the bus from Detroit Bus Station to Mississaugabus bus
    27h 51m
    $418–731

  4. Drive 1,162.8 km

    1. Drive from Knoxville to Mississaugacar car 1,162.8 km
    12h 28m
    $230–332

  5. Fly to Toronto Island Airport

    1. Fly from Mcghee Tyson Airport (TYS) to Toronto Island Airport (YTZ)plane plane TYS - YTZ
    6h 27m
    $227–854

  6. Fly to Buffalo Niagara International Airport, shuttle

    1. Fly from Mcghee Tyson Airport (TYS) to Buffalo Niagara International Airport (BUF)plane plane TYS - BUF
    2. Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1shuttle bus
    7h 17m
    $444–1,560

  7. Bus

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to El Mercadito Grocery - Clarksville, INbus bus
    3. Take the bus from Louisville Bus Station to Detroit Bus Stationbus bus
    4. Take the bus from Detroit Bus Station to Mississaugabus bus
    28h 18m
    $444–762

Mcghee Tyson Airport (TYS) to Toronto Pearson International Airport (YYZ) flights

Calendar129Weekly Planes
Duration5h 9mAverage Duration
Ticket$124Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Mississauga.ExpandLaunch map view
  • Distance: 986.6 km
  • Duration: 5h

What companies run services between Knoxville, TN, USA and Mississauga, ON, Canada?

Delta, United Airlines, and American Airlines fly from Mcghee Tyson Airport (TYS) to Toronto Pearson International Airport (YYZ) hourly. Alternatively, you can take a vehicle from Knoxville to Mississauga via Knoxville, Jackson, El Mezcal Grocery - Jackson, TN, Indianapolis, Indianapolis, IN, and Detroit Bus Station in around 27h 51m.

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