What is the cheapest way to get from Knoxville to Mount Pleasant?

The cheapest way to get from Knoxville to Mount Pleasant is to drive which costs $65 - $100 and takes 6h 27m.

What is the fastest way to get from Knoxville to Mount Pleasant?

The fastest way to get from Knoxville to Mount Pleasant is to drive which takes 6h 27m and costs $65 - $100.

How far is it from Knoxville to Mount Pleasant?

The distance between Knoxville and Mount Pleasant is 339 miles. The road distance is 377.9 miles.

How long does it take to get from Knoxville to Mount Pleasant?

It takes approximately 6h 34m to get from Knoxville to Mount Pleasant, including transfers.

Can I drive from Knoxville to Mount Pleasant?

Yes, the driving distance between Knoxville to Mount Pleasant is 378 miles. It takes approximately 6h 27m to drive from Knoxville to Mount Pleasant.

Where can I stay near Mount Pleasant?

There are 1577+ hotels available in Mount Pleasant.

Knoxville to Mount Pleasant - 3 ways to travel via plane, bus, and car

How to get fromKnoxville to Mount Pleasant

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There are 3 ways to get from Knoxville to Mount Pleasant by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly
best
1. Fly from Mcghee Tyson Airport (TYS) to Charleston International Airport (CHS)plane TYS - CHS
6h 34m
$136–551
Drive 375.7 mi
cheapest
1. Drive from Knoxville to Mount Pleasantcar 375.7 mi
6h 27m
$69–99
Bus, drive
1. Take the bus from Knoxville to Nashvillebus Nyc
2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus
3. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus
4. Drive from Myrtle Beach Bus Station to S. Pinckney St / Society Rdcar
5. Take the bus from S. Pinckney St / Society Rd to Stuart Engals Blvd / Wando Crossing Centerbus
22h 34m
$234–368

Mcghee Tyson Airport (TYS) to Charleston International Airport (CHS) flights

104Weekly Planes

4h 29mAverage Duration

$77Cheapest Price

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Questions & Answers

Map of how to get from Knoxville to Mount Pleasant.

Launch map view

Distance: 337 mi
Duration: 6h 34m

What companies run services between Knoxville, TN, USA and Mount Pleasant, SC, USA?

Delta, American Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Charleston International Airport (CHS) hourly.

Airlines

Bus operators

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How to get fromKnoxville to Mount Pleasantby plane, bus, or car

There are 3 ways to get from Knoxville to Mount Pleasant by plane, bus, or car

Fly

Drive 375.7 mi

Bus, drive