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How to get fromKnoxville to Nacogdochesby plane, car, bus (Greyhound, Flixbus), bus, or train

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There are 7 ways to get from Knoxville to Nacogdoches by plane, car, bus (Greyhound, Flixbus), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Tyler, drive

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Tyler (TYR)plane plane TYS - TYR
    2. Drive from Tyler (TYR) to Nacogdochescar car
    6h 29m
    $191–689

  2. Drive 801.7 mi

    cheapest
    1. Drive from Knoxville to Nacogdochescar car 801.7 mi
    13h 25m
    $147–212

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Texarkanabus bus
    3. Take the bus from Texarkana to Nacogdochesbus bus
    19h 52m
    $253–398

  4. Bus, train

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Longviewtrain train
    4. Take the bus from Longview to Nacogdoches Amtrak Bus Stopbus bus
    28h
    $405–715

  5. Fly to Gregg County Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Gregg County Airport (GGG)plane plane TYS - GGG
    2. Take the bus from Longview Bus Station to Nacogdochesbus bus
    8h 53m
    $220–778

  6. Fly to Shreveport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Shreveport (SHV)plane plane TYS - SHV
    2. Take the bus from Shreveport Bus Station to Nacogdochesbus bus
    9h 16m
    $191–676

  7. Fly to George Bush Intercontinental Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to George Bush Intercontinental Airport (IAH)plane plane TYS - IAH
    2. Take the bus from Houston Bus Station to Nacogdochesbus bus
    8h 45m
    $217–787

Mcghee Tyson Airport (TYS) to Tyler (TYR) flights

Calendar21Weekly Planes
Duration4h 49mAverage Duration
Ticket$125Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Nacogdoches.ExpandLaunch map view
  • Distance: 789 mi
  • Duration: 6h 29m

What companies run services between Knoxville, TN, USA and Nacogdoches, TX, USA?

You can take a vehicle from Knoxville to Nacogdoches via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, Texarkana, and Nacogdoches in around 19h 52m.

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