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How to get fromKnoxville to Natchezby plane, car, bus, train, or taxi

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There are 8 ways to get from Knoxville to Natchez by plane, car, bus, train, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Baton Rouge Metropolitan Airport, drive

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Baton Rouge Metropolitan Airport (BTR)plane plane TYS - BTR
    2. Drive from Baton-Rouge-Airport-BTR to Natchezcar car
    5h 50m
    $152–530

  2. Drive  591.6 mi

    cheapest
    1. Drive from Knoxville to Natchezcar car 591.6 mi
    10h 19m
    $108–156

  3. Bus, train, drive via New South Memphis

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Jacksonbus bus
    4. Take the train from Jackson to Brookhaven Stationtrain train
    5. Drive from Brookhaven Station to Natchezcar car
    16h 19m
    $218–331

  4. Bus, train, drive

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the train from Carbondale to Brookhaven Stationtrain train
    4. Drive from Brookhaven Station to Natchezcar car
    21h 54m
    $294–526

  5. Fly to Alexandria International Airport, taxi

    1. Fly from Mcghee Tyson Airport (TYS) to Alexandria International Airport (AEX)plane plane TYS - AEX
    2. Take the taxi from Alexandria International Airport (AEX) to Natcheztaxi taxi
    6h 47m
    $159–553

  6. Fly to Natchez

    1. Fly from Mcghee Tyson Airport (TYS) to Natchez (HEZ)plane plane TYS - HEZ
    7h 44m
    $195–652

  7. Fly to Monroe Regional Airport, taxi

    1. Fly from Mcghee Tyson Airport (TYS) to Monroe Regional Airport (MLU)plane plane TYS - MLU
    2. Take the taxi from Monroe Regional Airport (MLU) to Natcheztaxi taxi
    6h 14m
    $159–533

  8. Fly to Jackson/Vicksburg, train, drive

    1. Fly from Mcghee Tyson Airport (TYS) to Jackson/Vicksburg (JAN)plane plane TYS - JAN
    2. Take the train from Jackson to Brookhaven Stationtrain train
    3. Drive from Brookhaven Station to Natchezcar car
    7h
    $192–589

Mcghee Tyson Airport (TYS) to Baton Rouge Metropolitan Airport (BTR) flights

Calendar26Weekly Planes
Duration4h 10mAverage Duration
Ticket$80Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Knoxville to Natchez.ExpandLaunch map view
  • Distance: 648.7 mi
  • Duration: 5h 50m

What companies run services between Knoxville, TN, USA and Natchez, MS, USA?

United Airlines flies from Mcghee Tyson Airport (TYS) to Natchez (HEZ) once daily.

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