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How to get fromKnoxville to New Buffaloby plane, train, bus (Greyhound, Flixbus, Amtrak), or car

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There are 7 ways to get from Knoxville to New Buffalo by plane, train, bus (Greyhound, Flixbus, Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mcghee Tyson Airport to Chicago O'Hare International Airport, train

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Chicago O'Hare International Airport (ORD)plane plane TYS - ORD
    2. Take the train from Chicago Union Station to New Buffalo Stationtrain train
    5h 38m
    $137–410

  2. Drive  500.7 mi

    cheapest
    1. Drive from Knoxville to New Buffalocar car 500.7 mi
    9h 26m
    $86–124

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Union Station to New Buffalo Stationbus bus
    17h 14m

  4. Fly Mcghee Tyson Airport to South Bend, train

    1. Fly from Mcghee Tyson Airport (TYS) to South Bend (SBN)plane plane TYS - SBN
    2. Take the train from South Bend Airport to Carroll Avetrain train
    6h 12m
    $160–487

  5. Drive to Chattanooga Metropolitan Airport, fly to Chicago O'Hare International Airport, train

    1. Drive from Knoxville to Chattanooga Metropolitan Airport (CHA)car car
    2. Fly from Chattanooga Metropolitan Airport (CHA) to Chicago O'Hare International Airport (ORD)plane plane CHA - ORD
    3. Take the train from Chicago Union Station to New Buffalo Stationtrain train
    7h 11m
    $98–368

  6. Drive to Asheville Regional Airport, fly to Chicago O'Hare International Airport, train

    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Chicago O'Hare International Airport (ORD)plane plane AVL - ORD
    3. Take the train from Chicago Union Station to New Buffalo Stationtrain train
    7h 37m
    $101–383

  7. Fly Mcghee Tyson Airport to Chicago Midway International Airport, train

    1. Fly from Mcghee Tyson Airport (TYS) to Chicago Midway International Airport (MDW)plane plane TYS - MDW
    2. Take the train from Chicago Union Station to New Buffalo Stationtrain train
    5h 3m
    $154–517

Mcghee Tyson Airport (TYS) to Chicago O'Hare International Airport (ORD) flights

Calendar89Weekly Planes
Duration3h 10mAverage Duration
Ticket$46Cheapest Price
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Comparing Your Travel Options

Map of how to get from Knoxville to New Buffalo.ExpandLaunch map view
  • Distance: 568.2 mi
  • Duration: 5h 38m

What companies run services between Knoxville, TN, USA and New Buffalo, MI, USA?

You can take a vehicle from Knoxville to New Buffalo Station via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, Chicago Bus Station, and Chicago Union Station in around 17h 14m.

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