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How to get fromKnoxville to North Charlestonby plane, car, shuttle, bus, or taxi

Find Transport to North Charleston

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There are 4 ways to get from Knoxville to North Charleston by plane, car, shuttle, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Charleston International Airport (CHS)plane plane TYS - CHS
    4h 39m
    $134–549

  2. Drive 366.1 mi

    cheapest
    1. Drive from Knoxville to North Charlestoncar car 366.1 mi
    6h 16m
    $67–97

  3. Drive, shuttle, bus

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    4. Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus bus
    5. Take the bus from Charlotte Bus Station to Charleston Bus Stationbus bus
    16h 10m
    $369–442

  4. Drive, shuttle, taxi, bus

    1. Drive from Chilhowee at Holston to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to ASU Peacock Hall Boonetaxi taxi
    4. Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus bus
    5. Take the bus from Charlotte Bus Station to Charleston Bus Stationbus bus
    16h 32m
    $404–507

Mcghee Tyson Airport (TYS) to Charleston International Airport (CHS) flights

Calendar106Weekly Planes
Duration4h 29mAverage Duration
Ticket$77Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to North Charleston.ExpandLaunch map view
  • Distance: 322.3 mi
  • Duration: 4h 39m

What companies run services between Knoxville, TN, USA and North Charleston, SC, USA?

Delta, American Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Charleston International Airport (CHS) hourly.

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