There are 5 ways to get from Knoxville to Ocean Springs by plane, bus (Greyhound), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Mcghee Tyson Airport (TYS) to Gulfport-Biloxi Regional Airport (GPT)plane TYS - GPT
4h 14m$162–482Drive 551.4 mi
cheapest- Drive from Knoxville to Ocean Springscar 551.4 mi
9h 34m$95–137Bus
- Take the bus from Knoxville to Nashvillebus Nyc
- Take the bus from Nashville Bus Station to Montgomery Intermodal Centerbus
- Take the bus from Montgomery Intermodal Center to Biloxi Transit Centerbus
16h 47m$225–316Bus via Clarksville Exit 11 Park And Ride
- Take the bus from Knoxville to Nashvillebus Nyc
- Take the bus from Central 5Th Ave - Bay 11 to Clarksville Exit 11 Park And Ridebus 94
- Take the bus from Clarksville Park & Ride to Montgomery Intermodal Centerbus
- Take the bus from Montgomery Intermodal Center to Biloxi Transit Centerbus
20h 33m$230–326Bus, train
- Take the bus from Knoxville to Memphis - Summer Avebus Nyc
- Take the bus from Memphis Bus Station to New Orleans Bus Stationbus
- Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain
23h 39m$252–378
Mcghee Tyson Airport (TYS) to Gulfport-Biloxi Regional Airport (GPT) flights
Comparing Your Travel Options
The cheapest way to get from Knoxville to Ocean Springs is to drive which costs $90 - $140 and takes 9h 34m.
The fastest way to get from Knoxville to Ocean Springs is to fly which takes 4h 14m and costs $160 - $490.
No, there is no direct bus from Knoxville to Ocean Springs. However, there are services departing from Knoxville and arriving at Visitor Center / Villa Maria via Charlotte Pike & Lellyett St Eb, Central 4Th Ave - Bay 13, Nashville Bus Station, Montgomery Intermodal Center and Biloxi Transit Center. The journey, including transfers, takes approximately 16h 47m.
The distance between Knoxville and Ocean Springs is 507 miles. The road distance is 554.6 miles.
The best way to get from Knoxville to Ocean Springs without a car is to bus which takes 16h 47m and costs $220 - $320.
It takes approximately 4h 14m to get from Knoxville to Ocean Springs, including transfers.
Knoxville to Ocean Springs bus services, operated by Wanda Coach, depart from Knoxville station.
The best way to get from Knoxville to Ocean Springs is to fly which takes 4h 14m and costs $160 - $490. Alternatively, you can bus, which costs $220 - $320 and takes 16h 47m.
Knoxville to Ocean Springs bus services, operated by Wanda Coach, arrive at Nashville station.
Ocean Springs is 1h behind Knoxville. It is currently 3:11 PM in Knoxville and 2:11 PM in Ocean Springs.
What companies run services between Knoxville, TN, USA and Ocean Springs, MS, USA?
Delta, American Airlines, and United Airlines fly from Mcghee Tyson Airport (TYS) to Gulfport-Biloxi Regional Airport (GPT) every 2 hours. Alternatively, you can take a vehicle from Knoxville to Visitor Center / Villa Maria via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, Montgomery Intermodal Center, and Biloxi Transit Center in around 16h 47m.
- Website
- aa.com
Flights from Mcghee Tyson Airport to Gulfport-Biloxi Regional Airport via Charlotte
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $75–410
Flights from Mcghee Tyson Airport to Gulfport-Biloxi Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 55m
- When
- Every day
- Estimated price
- $100–500
- Website
- delta.com
Flights from Mcghee Tyson Airport to Gulfport-Biloxi Regional Airport via Atlanta
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $60–360
- Website
- united.com
Flights from Mcghee Tyson Airport to Gulfport-Biloxi Regional Airport via Houston
- Ave. Duration
- 6h 13m
- When
- Every day
- Estimated price
- $95–480
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Biloxi Amtrak Sta
- Ave. Duration
- 1h 23m
- Frequency
- Twice daily
- Estimated price
- $40–70
- Website
- Amtrak
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from Knoxville to Nashville
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $40–60
Bus from Knoxville to Nashville
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $40–60
Bus from Knoxville to Memphis - Summer Ave
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $55–80
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $55–80
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Nashville Bus Station to Montgomery Intermodal Center
- Ave. Duration
- 5h 5m
- Frequency
- Twice daily
- Estimated price
- $50–80
- Website
- Greyhound
Bus from Montgomery Intermodal Center to Biloxi Transit Center
- Ave. Duration
- 4h 35m
- Frequency
- Twice daily
- Estimated price
- $40–65
- Website
- Greyhound
Bus from Clarksville Park & Ride to Montgomery Intermodal Center
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $55–90
- Website
- Greyhound
Bus from Montgomery Intermodal Center to Biloxi Transit Center
- Ave. Duration
- 4h 35m
- Frequency
- Twice daily
- Estimated price
- $40–65
- Website
- Greyhound
Bus from Memphis Bus Station to New Orleans Bus Station
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- $75–120
- Website
- Greyhound
- Phone
- +1 615-862-5950
- Website
- WeGo Transit
Bus from Central 5Th Ave - Bay 11 to Clarksville Exit 11 Park And Ride
- Ave. Duration
- 52 min
- Frequency
- Every 4 hours
- Estimated price
- $2
- Website
- WeGo Transit
- Adult
- $2
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Memphis Bus Station to New Orleans Bus Station
- Ave. Duration
- 8h 10m
- Frequency
- 5 times a week
- Estimated price
- $65–100
- Schedules at
- Flixbus USA
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Booking & Getting There
Yes, the driving distance between Knoxville to Ocean Springs is 555 miles. It takes approximately 9h 34m to drive from Knoxville to Ocean Springs.
There are 217+ hotels available in Ocean Springs.







