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How to get fromKnoxville to Orlandoby plane, bus (Greyhound, Flixbus), car, shuttle, taxi, bus, or train

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There are 7 ways to get from Knoxville to Orlando by plane, bus (Greyhound, Flixbus), car, shuttle, taxi, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mcghee Tyson Airport to Orlando

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Orlando (MCO)plane plane TYS - MCO
    2h 17m
    $144–549

  2. Drive to Asheville Regional Airport, fly to Orlando

    cheapest
    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Orlando (MCO)plane plane AVL - MCO
    4h 12m
    $79–364

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta - Civic Center MARTA Station to Orlando RedCoach Stationbus bus
    18h 12m
    $281–467

  4. Drive, shuttle, taxi, bus, train

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Boonetaxi taxi
    4. Take the bus from Boone to Forsyth Hospitalbus bus
    5. Take the train from High Point to Carytrain train
    6. Take the train from Cary to Orlandotrain train
    26h 5m

  5. Drive 635 mi

    1. Drive from Knoxville to Orlandocar car 635 mi
    10h 44m
    $116–168

  6. Fly Mcghee Tyson Airport to Orlando Sanford

    1. Fly from Mcghee Tyson Airport (TYS) to Orlando Sanford (SFB)plane plane TYS - SFB
    2h 27m
    $202–632

  7. Drive, shuttle, bus

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    4. Take the bus from Boone to Charlottebus bus
    5. Take the bus from Charlotte Bus Station to Orlando Bus Stationbus bus
    20h 24m

Mcghee Tyson Airport (TYS) to Orlando (MCO) flights

Calendar43Weekly Planes
Duration3h 16mAverage Duration
Ticket$89Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Orlando.ExpandLaunch map view
  • Distance: 551.3 mi
  • Duration: 2h 17m

What companies run services between Knoxville, TN, USA and Orlando, FL, USA?

Allegiant Air, Southwest Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Orlando (MCO) every 4 hours. Alternatively, you can take a vehicle from Knoxville to Orlando RedCoach Station via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, Atlanta Bus Station, Garnett Station, Civic Center Station, and Atlanta - Civic Center MARTA Station in around 18h 12m.

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