There are 6 ways to get from Knoxville to Orlando by plane, bus (Greyhound, Flixbus), car, shuttle, taxi, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Orlando
best- Fly from Mcghee Tyson Airport (TYS) to Orlando (MCO)plane TYS - MCO
2h 23m$149–619Drive 634.9 mi
cheapest- Drive from Knoxville to Orlandocar 634.9 mi
10h 44m$116–168Bus
- Take the bus from Knoxville to Nashvillebus Nyc
- Take the bus from Nashville Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Orlando Bus Stationbus
18h 9m$233–354Drive, shuttle, taxi, bus, train
- Drive from Knoxville to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take the taxi from Black Bear Resort to Boonetaxi
- Take the bus from Boone to Forsyth Hospitalbus
- Take the train from High Point to Carytrain
- Take the train from Cary to Orlandotrain
26h 5m$670–952Fly to Orlando Sanford
- Fly from Mcghee Tyson Airport (TYS) to Orlando Sanford (SFB)plane TYS - SFB
2h 25m$197–612Drive, shuttle, bus
- Drive from Knoxville to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Boone
- Take the bus from Boone to Charlottebus
- Take the bus from Charlotte Bus Station to Orlando Bus Stationbus
20h 24m$332–395
Mcghee Tyson Airport (TYS) to Orlando (MCO) flights
Comparing Your Travel Options
The cheapest way to get from Knoxville to Orlando is to drive which costs $110 - $170 and takes 10h 44m.
The fastest way to get from Knoxville to Orlando is to fly which takes 2h 23m and costs $140 - $650.
No, there is no direct bus from Knoxville to Orlando station. However, there are services departing from Knoxville and arriving at Orlando Bus Station via Charlotte Pike & Lellyett St Eb, Central 4Th Ave - Bay 13, Nashville Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 18h 9m.
The distance between Knoxville and Orlando is 555 miles. The road distance is 638.7 miles.
The best way to get from Knoxville to Orlando without a car is to bus which takes 18h 9m and costs $230 - $360.
It takes approximately 2h 23m to get from Knoxville to Orlando, including transfers.
Knoxville to Orlando bus services, operated by Wanda Coach, depart from Knoxville station.
The best way to get from Knoxville to Orlando is to fly which takes 2h 23m and costs $140 - $650. Alternatively, you can bus, which costs $230 - $360 and takes 18h 9m.
Knoxville to Orlando bus services, operated by Wanda Coach, arrive at Nashville station.
Yes, the driving distance between Knoxville to Orlando is 639 miles. It takes approximately 10h 44m to drive from Knoxville to Orlando.
What companies run services between Knoxville, TN, USA and Orlando, FL, USA?
Allegiant Air, Southwest Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Orlando (MCO) every 3 hours. Alternatively, you can take a vehicle from Knoxville to Orlando Bus Station via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, and Atlanta Bus Station in around 18h 9m.
- Website
- allegiantair.com
Flights from Mcghee Tyson Airport to Orlando
- Ave. Duration
- 1h 41m
- When
- Monday and Friday
- Estimated price
- $90–550
Flights from Mcghee Tyson Airport to Orlando Sanford
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $80–470
- Website
- delta.com
Flights from Mcghee Tyson Airport to Orlando via Atlanta
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $90–550
- Website
- aa.com
Flights from Mcghee Tyson Airport to Orlando via Charlotte
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $100–550
- Website
- southwest.com
Flights from Mcghee Tyson Airport to Orlando
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $90–550
Flights from Mcghee Tyson Airport to Orlando via Nashville
- Ave. Duration
- 4h
- When
- Saturday
- Estimated price
- $110–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from High Point to Cary
- Ave. Duration
- 1h 46m
- Frequency
- 4 times a day
- Estimated price
- $45–75
- Website
- Amtrak
Train from Cary to Orlando
- Ave. Duration
- 13h 49m
- Frequency
- Once daily
- Estimated price
- $340–550
- Website
- Amtrak
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from Knoxville to Nashville
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $40–60
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–65
- Website
- Greyhound
Bus from Atlanta Bus Station to Orlando Bus Station
- Ave. Duration
- 9h 50m
- Frequency
- Once daily
- Estimated price
- $75–120
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Orlando Bus Station
- Ave. Duration
- 7h 45m
- Frequency
- Every 4 hours
- Estimated price
- $65–110
- Schedules at
- Flixbus USA
Bus from Charlotte Bus Station to Orlando Bus Station
- Ave. Duration
- 10h 15m
- Frequency
- Once daily
- Estimated price
- $80–130
- Schedules at
- Flixbus USA
- Phone
- +1-423-725-5988
- Website
- Black Bear Resort Shuttle
Shuttle from Hot Springs to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- Black Bear Resort Shuttle
Shuttle from Hot Springs to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- Black Bear Resort Shuttle
Shuttle from Black Bear Resort to Boone
- Ave. Duration
- 1h
- Frequency
- On demand
- Estimated price
- $86
- Website
- Black Bear Resort Shuttle
- Phone
- +1 704-348-1200
- [email protected]
- Website
- Sunway Charters
Bus from Boone to Forsyth Hospital
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $13–19
- Schedules at
- Sunway Charters
- Passenger
- $13–19
Bus from Boone to Charlotte
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $17–24
- Schedules at
- Sunway Charters
- Passenger
- $17–24
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
There are 2034+ hotels available in Orlando.








