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How to get fromKnoxville to Palatineby plane, train, bus, or car

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There are 6 ways to get from Knoxville to Palatine by plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mcghee Tyson Airport to Chicago O'Hare International Airport, train

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Chicago O'Hare International Airport (ORD)plane plane TYS - ORD
    2. Take the train from Irving Park to Palatinetrain train
    3h 57m
    $133–468

  2. Drive to Asheville Regional Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Chicago O'Hare International Airport (ORD)plane plane AVL - ORD
    6h
    $78–333

  3. Bus, train

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville to Chicago Union Stationbus bus
    3. Take the train from Chicago OTC to Palatinetrain train
    16h 11m
    $210–318

  4. Drive 554 mi

    1. Drive from Knoxville to Palatinecar car 554 mi
    9h 51m
    $102–146

  5. Fly Mcghee Tyson Airport to Chicago Midway International Airport, train

    1. Fly from Mcghee Tyson Airport (TYS) to Chicago Midway International Airport (MDW)plane plane TYS - MDW
    2. Take the train from Chicago OTC to Palatinetrain train
    4h 10m
    $143–528

  6. Drive to Chattanooga Metropolitan Airport, fly to Chicago O'Hare International Airport

    1. Drive from Knoxville to Chattanooga Metropolitan Airport (CHA)car car
    2. Fly from Chattanooga Metropolitan Airport (CHA) to Chicago O'Hare International Airport (ORD)plane plane CHA - ORD
    5h 33m
    $105–488

Mcghee Tyson Airport (TYS) to Chicago O'Hare International Airport (ORD) flights

Calendar85Weekly Planes
Duration3h 13mAverage Duration
Ticket$69Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Palatine.ExpandLaunch map view
  • Distance: 517.6 mi
  • Duration: 3h 57m

What companies run services between Knoxville, TN, USA and Palatine, IL, USA?

There is no direct connection from Knoxville to Palatine. However, you can take the taxi to Mcghee Tyson Airport (TYS) airport, fly to Chicago O'Hare International Airport (ORD), walk to O'Hare, take the subway to Irving Park-Blue, walk to Irving Park, then take the train to Palatine. Alternatively, you can take a vehicle from Knoxville to Palatine via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville, Chicago Union Station, Clinton & Quincy, Washington & Canal, and Chicago OTC in around 16h 11m.

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