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How to get fromKnoxville to Palermoby plane, car, or bus

Find Transport to Palermo

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There are 5 ways to get from Knoxville to Palermo by plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mcghee Tyson Airport to Palermo Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Palermo Airport (PMO)plane plane TYS - PMO
    16h
    €374–1,266

  2. Drive to Asheville Regional Airport, fly to Palermo Airport

    cheapest
    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Palermo Airport (PMO)plane plane AVL - PMO
    16h 41m
    €263–934

  3. Drive to Chattanooga Metropolitan Airport, fly to Palermo Airport

    1. Drive from Knoxville to Chattanooga Metropolitan Airport (CHA)car car
    2. Fly from Chattanooga Metropolitan Airport (CHA) to Palermo Airport (PMO)plane plane CHA - PMO
    15h 22m
    €270–930

  4. Fly Mcghee Tyson Airport to Catania–Fontanarossa Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Catania–Fontanarossa Airport (CTA)plane plane TYS - CTA
    2. Take the bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazellobus bus
    16h 52m
    €362–1,186

  5. Drive to Greenville–Spartanburg International Airport, fly to Palermo Airport

    1. Drive from Knoxville to Greenville–Spartanburg International Airport (GSP)car car
    2. Fly from Greenville–Spartanburg International Airport (GSP) to Palermo Airport (PMO)plane plane GSP - PMO
    18h 34m
    €301–1,047

Mcghee Tyson Airport (TYS) to Palermo Airport (PMO) flights

Calendar4Weekly Planes
Duration15h 45mAverage Duration
Ticket€323Cheapest Price
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Comparing Your Travel Options

Map of how to get from Knoxville to Palermo.ExpandLaunch map view
  • Distance: 8,230.7 km
  • Duration: 16h

What companies run services between Knoxville, TN, USA and Palermo, Italy?

United Airlines and ITA Airways fly from Mcghee Tyson Airport (TYS) to Palermo Airport (PMO) 4 times a week.

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