Rome2Rio

How to get fromKnoxville to Palermoby car, plane, or bus

Find Transport to Palermo

See all options

There are 4 ways to get from Knoxville to Palermo by car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Asheville Regional Airport, fly to Palermo Airport

    best
    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Palermo Airport (PMO)plane plane AVL - PMO
    18h 44m
    €332–934
  2. Fly Mcghee Tyson Airport to Palermo Airport

    1. Fly from Mcghee Tyson Airport (TYS) to Palermo Airport (PMO)plane plane TYS - PMO
    19h 15m
    €502–1,365
  3. Drive to Greenville–Spartanburg International Airport, fly to Palermo Airport

    1. Drive from Knoxville to Greenville–Spartanburg International Airport (GSP)car car
    2. Fly from Greenville–Spartanburg International Airport (GSP) to Palermo Airport (PMO)plane plane GSP - PMO
    18h 1m
    €390–1,346
  4. Fly Mcghee Tyson Airport to Trapani Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Trapani Airport (TPS)plane plane TYS - TPS
    2. Take the bus from Trapani Birgi Airport to Palermo Via Belgio/Via dei Nebrodibus bus
    17h 37m
    €605–1,668

Asheville Regional Airport (AVL) to Palermo Airport (PMO) flights

Calendar12Weekly Planes
Duration19h 43mAverage Duration
Ticket€286Cheapest Price
See schedules

Questions & Answers

What companies run services between Knoxville, TN, USA and Palermo, Italy?

Allegiant Air, United Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Palermo Airport (PMO) once daily.

Airlines
Bus operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides