There are 4 ways to get from Knoxville to Picayune by plane, taxi, bus (Greyhound), car, shuttle, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, taxi
best- Fly from Mcghee Tyson Airport (TYS) to Gulfport-Biloxi Regional Airport (GPT)plane TYS - GPT
- Take the taxi from Gulfport-Biloxi Regional Airport (GPT) to Picayunetaxi
4h 40m$267–807Drive 550.1 mi
cheapest- Drive from Knoxville to Picayunecar 550.1 mi
9h$101–145Bus
- Take the bus from Knoxville to Memphis - Summer Avebus Nyc
- Take the bus from Memphis Bus Station to Slidellbus Greyhound US1173 / ...
19h 36m$260–376Drive, shuttle, taxi, bus, train
- Drive from Knoxville to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take the taxi from Black Bear Resort to Blowing Rock - Tanger Outletstaxi
- Take the bus from Blowing Rock - Tanger Outlets to Hickory Airportbus
- Take the bus from Hickory Airport to Charlotte Airportbus
- Take the train from Charlotte Amtrak Station to Picayune Amtrak Stationtrain
27h 8m$605–921
Mcghee Tyson Airport (TYS) to Gulfport-Biloxi Regional Airport (GPT) flights
Questions & Answers
The cheapest way to get from Knoxville to Picayune is to drive which costs $100 - $150 and takes 9h.
The fastest way to get from Knoxville to Picayune is to fly and taxi which takes 4h 40m and costs $260 - $850.
No, there is no direct bus from Knoxville to Picayune. However, there are services departing from Knoxville and arriving at Slidell via SUMMER AVENUE at WHITE STATION ROAD, William Hudson Transit Center and Memphis Bus Station. The journey, including transfers, takes approximately 19h 36m.
The distance between Knoxville and Picayune is 535 miles. The road distance is 553.3 miles.
The best way to get from Knoxville to Picayune without a car is to bus which takes 19h 36m and costs $260 - $380.
It takes approximately 4h 40m to get from Knoxville to Picayune, including transfers.
Knoxville to Picayune bus services, operated by Wanda Coach, depart from Knoxville station.
Knoxville to Picayune bus services, operated by Wanda Coach, arrive at Memphis - Summer Ave station.
Picayune is 1h behind Knoxville. It is currently 7:34 AM in Knoxville and 6:34 AM in Picayune.
Yes, the driving distance between Knoxville to Picayune is 553 miles. It takes approximately 9h to drive from Knoxville to Picayune.
What companies run services between Knoxville, TN, USA and Picayune, MS, USA?
You can take a vehicle from Knoxville to Picayune via Knoxville, Memphis - Summer Ave, SUMMER AVENUE at WHITE STATION ROAD, William Hudson Transit Center, AIRWAYS BOULEVARD at BROOKS ROAD, Memphis Bus Station, and Slidell in around 19h 36m.
- Website
- aa.com
Flights from Mcghee Tyson Airport to Gulfport-Biloxi Regional Airport via Charlotte
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $130–650
Flights from Mcghee Tyson Airport to Gulfport-Biloxi Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 24m
- When
- Every day
- Estimated price
- $190–850
- Website
- delta.com
Flights from Mcghee Tyson Airport to Gulfport-Biloxi Regional Airport via Atlanta
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $100–600
- Website
- united.com
Flights from Mcghee Tyson Airport to Gulfport-Biloxi Regional Airport via Houston
- Ave. Duration
- 6h 3m
- When
- Every day
- Estimated price
- $170–800
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Charlotte Amtrak Station to Picayune Amtrak Station
- Ave. Duration
- 17h
- Frequency
- Once daily
- Estimated price
- $230–480
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 646-630-7186
- [email protected]
- Website
- wandacoach.com
Bus from Knoxville to Memphis - Summer Ave
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $55–80
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $55–80
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Memphis Bus Station to Slidell
- Ave. Duration
- 8h 10m
- Frequency
- Twice daily
- Estimated price
- $90–130
- Book at
- https://www.jeffersonlines.com
- Adult
- $90–130
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Memphis Bus Station to Slidell
- Ave. Duration
- 8h 10m
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- https://www.greyhound.com/
- Phone
- +1-423-725-5988
- Website
- blackbearresorttn.com
Shuttle from Hot Springs to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- https://blackbearresorttn.com/Shuttle-Service.html
- Phone
- +1 828-327-2340
- [email protected]
- Website
- hickoryhop.com
Bus from Blowing Rock - Tanger Outlets to Hickory Airport
- Ave. Duration
- 59 min
- Frequency
- Every 4 hours
- Estimated price
- $30–45
- Schedules at
- hickoryhop.com
Bus from Hickory Airport to Charlotte Airport
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $50–65
- Schedules at
- hickoryhop.com
- Ave. Duration
- 1h 13m
- Estimated price
- $110–170
Gulf Coast Yellow Cab
- Phone
- +1-228-385-7777
Reliable Taxi
- Phone
- +1-423-426-6003
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 13+ hotels available in Picayune.











