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How to get fromKnoxville to Picayuneby plane, taxi, bus, train, car, or bus (Greyhound)

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There are 5 ways to get from Knoxville to Picayune by plane, taxi, bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Gulfport-Biloxi Regional Airport, taxi

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Gulfport-Biloxi Regional Airport (GPT)plane plane TYS - GPT
    2. Take the taxi from Gulfport-Biloxi Regional Airport (GPT) to Picayunetaxi taxi
    5h 4m
    $247–697

  2. Drive  550.1 mi

    cheapest
    1. Drive from Knoxville to Picayunecar car 550.1 mi
    8h 59m
    $101–145

  3. Bus, train

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to Jacksonbus bus
    3. Take the train from Jackson to New Orleans Union Passenger Terminaltrain train
    4. Take the train from New Orleans Union Passenger Terminal to Picayune Amtrak Stationtrain train
    19h 16m
    $262–425

  4. Fly to Louis Armstrong New Orleans International Airport, train

    1. Fly from Mcghee Tyson Airport (TYS) to Louis Armstrong New Orleans International Airport (MSY)plane plane TYS - MSY
    2. Take the train from New Orleans Union Passenger Terminal to Picayune Amtrak Stationtrain train
    7h 28m
    $173–702

  5. Bus

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to Slidellbus bus Greyhound US1173
    19h 36m
    $250–346

Mcghee Tyson Airport (TYS) to Gulfport-Biloxi Regional Airport (GPT) flights

Calendar81Weekly Planes
Duration4h 58mAverage Duration
Ticket$83Cheapest Price
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Comparing Your Travel Options

Map of how to get from Knoxville to Picayune.ExpandLaunch map view
  • Distance: 532.3 mi
  • Duration: 5h 4m

What companies run services between Knoxville, TN, USA and Picayune, MS, USA?

You can take a vehicle from Knoxville to Picayune via Knoxville, Memphis - Summer Ave, SUMMER AVENUE at WHITE STATION ROAD, William Hudson Transit Center, AIRWAYS BOULEVARD at BROOKS ROAD, Memphis Bus Station, and Slidell in around 19h 36m.

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