Rome2Rio

How to get fromKnoxville to Rochesterby plane, bus, train, car, or bus (Greyhound)

Find Transport to Rochester

See all options

There are 6 ways to get from Knoxville to Rochester by plane, bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Rochester (ROC)plane plane TYS - ROC
    4h 19m
    $242–1,086

  2. Drive  746.5 mi

    cheapest
    1. Drive from Knoxville to Rochestercar car 746.5 mi
    12h 55m
    $137–197

  3. Bus, train

    1. Take the bus from Knoxville, TN to New York, NYbus bus Ny
    2. Take the train from New York Penn Station to Rochestertrain train VIA Rail
    20h 34m
    $235–423

  4. Fly to Buffalo Niagara International Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Buffalo Niagara International Airport (BUF)plane plane TYS - BUF
    2. Take the bus from Buffalo Niagara International Airport to Rochester Bus Stopbus bus
    6h 12m
    $186–782

  5. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Rochester Bus Stopbus bus
    23h 29m
    $263–389

  6. Bus, train via Toledo

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus bus
    3. Take the bus from Indianapolis to Toledobus bus
    4. Take the train from Toledo to Rochestertrain train
    27h 25m
    $461–681

Mcghee Tyson Airport (TYS) to Rochester (ROC) flights

Calendar100Weekly Planes
Duration5h 18mAverage Duration
Ticket$178Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Knoxville to Rochester.ExpandLaunch map view
  • Distance: 623.9 mi
  • Duration: 4h 19m

What companies run services between Knoxville, TN, USA and Rochester, NY, USA?

United Airlines, Delta, and two other airlines fly from Mcghee Tyson Airport (TYS) to Rochester (ROC) hourly. Alternatively, you can take a vehicle from Knoxville to Rochester Bus Stop via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, and Cleveland Bus Station in around 23h 29m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There