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How to get fromKnoxville to Saint Paulby plane, bus, train, car, or bus (Greyhound, Flixbus)

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There are 6 ways to get from Knoxville to Saint Paul by plane, bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mcghee Tyson Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Minneapolis–Saint Paul International Airport (MSP)plane plane TYS - MSP
    3h 26m
    $199–820

  2. Drive to Asheville Regional Airport, fly

    cheapest
    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Minneapolis–Saint Paul International Airport (MSP)plane plane AVL - MSP
    5h 18m
    $124–585

  3. Bus, train

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Central 5Th Ave - Bay 11 to Clarksville Exit 11 Park And Ridebus bus 94
    3. Take the bus from Clarksville Park & Ride to Carbondale Intermodal Stationbus bus
    4. Take the train from Carbondale to Chicago Union Stationtrain train
    5. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    24h 46m
    $390–694

  4. Bus, train via Memphis

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Tornado Bus Co - West Memphisbus bus
    3. Take the bus from Tornado Bus Co - West Memphis to Water & Chicago - Circle Kbus bus
    4. Take the train from Milwaukee to St. Paul-Minneapolistrain train
    28h 4m
    $379–770

  5. Drive 925.8 mi

    1. Drive from Knoxville to Saint Paulcar car 925.8 mi
    15h 42m
    $169–245

  6. Bus

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Saint Paul Union Depotbus bus
    28h 21m
    $328–591

Mcghee Tyson Airport (TYS) to Minneapolis–Saint Paul International Airport (MSP) flights

Calendar97Weekly Planes
Duration4h 40mAverage Duration
Ticket$146Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Saint Paul.ExpandLaunch map view
  • Distance: 812.3 mi
  • Duration: 3h 26m

What companies run services between Knoxville, TN, USA and Saint Paul, MN, USA?

Delta, Southwest Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Minneapolis–Saint Paul International Airport (MSP) hourly. Alternatively, you can take a vehicle from Knoxville to Saint Paul Union Depot via Knoxville, Jackson, El Mezcal Grocery - Jackson, TN, Indianapolis, Indianapolis Union Station, and Chicago Bus Station in around 28h 21m.

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