Rome2Rio

How to get fromKnoxville to San Angeloby plane, bus (Greyhound, Flixbus), car, or bus (Greyhound)

Find Transport to San Angelo

See all options

There are 6 ways to get from Knoxville to San Angelo by plane, bus (Greyhound, Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mcghee Tyson Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to San Angelo Regional Airport (SJT)plane plane TYS - SJT
    5h 26m
    $227–772

  2. Drive to Asheville Regional Airport, fly

    cheapest
    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to San Angelo Regional Airport (SJT)plane plane AVL - SJT
    8h 36m
    $162–547

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Big Springbus bus
    4. Take the bus from Big Spring to Concho Valley Transit Districtbus bus
    26h 43m
    $301–495

  4. Drive 1,095 mi

    1. Drive from Knoxville to San Angelocar car 1,095 mi
    17h 57m
    $200–289

  5. Drive to Chattanooga Metropolitan Airport, fly

    1. Drive from Knoxville to Chattanooga Metropolitan Airport (CHA)car car
    2. Fly from Chattanooga Metropolitan Airport (CHA) to San Angelo Regional Airport (SJT)plane plane CHA - SJT
    6h 44m
    $199–782

  6. Bus via Memphis

    1. Take the bus from Knoxville to Jacksonbus bus Nyc
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Tornado Bus Co - West Memphisbus bus
    3. Take the bus from Tornado Bus Co - West Memphis to Dallas Jeffersonbus bus
    4. Take the bus from Dallas to Big Springbus bus
    5. Take the bus from Big Spring to Concho Valley Transit Districtbus bus
    28h 15m
    $347–641

Mcghee Tyson Airport (TYS) to San Angelo Regional Airport (SJT) flights

Calendar21Weekly Planes
Duration5h 8mAverage Duration
Ticket$137Cheapest Price
See schedules

Questions & Answers

Map of how to get from Knoxville to San Angelo.ExpandLaunch map view
  • Distance: 1,019.4 mi
  • Duration: 5h 26m

What companies run services between Knoxville, TN, USA and San Angelo, TX, USA?

American Airlines flies from Mcghee Tyson Airport (TYS) to San Angelo Regional Airport (SJT) 3 times a day. Alternatively, you can take a vehicle from Knoxville to Concho Valley Transit District via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, Dallas Bus Station, and Big Spring in around 26h 43m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers