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How to get fromKnoxville to San Luis Obispoby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 7 ways to get from Knoxville to San Luis Obispo by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mcghee Tyson Airport to San Luis Obispo County Regional Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to San Luis Obispo County Regional Airport (SBP)plane plane TYS - SBP
    8h 13m
    $228–769

  2. Drive to Asheville Regional Airport, fly to San Luis Obispo County Regional Airport

    cheapest
    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to San Luis Obispo County Regional Airport (SBP)plane plane AVL - SBP
    10h 55m
    $143–534

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Central 5Th Ave - Bay 11 to Clarksville Exit 11 Park And Ridebus bus 94
    3. Take the bus from Clarksville Park & Ride to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    5. Take the bus from Los Angeles Union Station to San Luis Obispo Railroad Museumbus bus
    2d 10h
    $482–849

  4. Bus, train via Kansas City

    1. Take the bus from Knoxville to Memphis - Summer Avebus bus Nyc
    2. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Kansas Citytrain train
    4. Take the train from Kansas City to Los Angelestrain train
    5. Take the train from Los Angeles to San Luis Obispotrain train
    2d 14h
    $914–1,855

  5. Drive 2,308.5 mi

    1. Drive from Knoxville to San Luis Obispocar car 2,308.5 mi
    36h 51m
    $422–609

  6. Fly Mcghee Tyson Airport to Santa Barbara Municipal Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Santa Barbara Municipal Airport (SBA)plane plane TYS - SBA
    2. Take the bus from Uc Santa Barbara Amtrak Bus Stop to San Luis Obispobus bus
    10h 26m
    $298–969

  7. Bus, train

    1. Take the bus from Knoxville to Jacksonbus bus
    2. Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus bus
    3. Take the train from Indianapolis to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    5. Take the train from Fullerton Amtrak Station to San Luis Obispotrain train
    3d
    $1,025–2,206

Mcghee Tyson Airport (TYS) to San Luis Obispo County Regional Airport (SBP) flights

Calendar27Weekly Planes
Duration7h 33mAverage Duration
Ticket$178Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to San Luis Obispo.ExpandLaunch map view
  • Distance: 2,065.3 mi
  • Duration: 8h 13m

What companies run services between Knoxville, TN, USA and San Luis Obispo, CA, USA?

United Airlines, American Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to San Luis Obispo County Regional Airport (SBP) 4 times a day. Alternatively, you can take a vehicle from Knoxville to San Luis Obispo Railroad Museum via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 5Th Ave - Bay 11, Clarksville Exit 11 Park And Ride, Clarksville Park & Ride, St Louis Bus Station, and Los Angeles Union Station in around 2d 10h.

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