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How to get fromKnoxville to South Carolinaby plane, taxi, car, shuttle, bus, or train

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There are 4 ways to get from Knoxville to South Carolina by plane, taxi, car, shuttle, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly, taxi

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Charlotte Douglas International Airport (CLT)plane plane TYS - CLT
    2. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    2h 15m
    $222–767

  2. Drive 372.6 mi

    cheapest
    1. Drive from Knoxville to Charlestoncar car 372.6 mi
    6h 22m
    $68–99

  3. Drive, shuttle, taxi, bus, train

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Bristol Exit 5 Park & Ride Lottaxi taxi
    4. Take the bus from Bristol Exit 5 Park & Ride Lot to Washington Union Stationbus bus
    5. Take the train from Washington Union Station to Charleston Amtrak Stationtrain train
    25h 14m
    $458–674

  4. Bus, train

    1. Take the bus from Knoxville, TN to New York, NYbus bus Ny
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    28h 8m
    $400–683

Mcghee Tyson Airport (TYS) to Charlotte Douglas International Airport (CLT) flights

Calendar66Weekly Planes
Duration1h 53mAverage Duration
Ticket$86Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to South Carolina.ExpandLaunch map view
  • Distance: 216.3 mi
  • Duration: 2h 15m

What companies run services between Knoxville, TN, USA and South Carolina, USA?

There is no direct connection from Knoxville to South Carolina. However, you can take the taxi to Mcghee Tyson Airport (TYS) airport, fly to Charlotte Douglas International Airport (CLT), then take the taxi to Rock Hill. Alternatively, you can drive to Hot Springs, take the shuttle to Black Bear Resort, take the taxi to Bristol Exit 5 Park & Ride Lot, take the bus to Washington Union Station, walk to Washington Union Station, take the train to Charleston Amtrak Station, walk to North Charleston Transit Center, take the line 104 bus to N. Charleston SuperStop, walk to Rivers Ave / Cosgrove Ave, take the line 10 bus to Transit Mall, walk to Visitors Center on John St, then take the line 211 bus to Broad St / Meeting St.

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