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How to get fromKnoxville to St. Louis Airport (STL)by plane, bus (Greyhound, Flixbus), rideshare, car, or bus (Flixbus, Amtrak)

Find Transport to St. Louis Airport (STL)

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There are 7 ways to get from Knoxville to St. Louis Airport (STL) by plane, bus (Greyhound, Flixbus), rideshare, car, or bus (Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mcghee Tyson Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Lambert–St. Louis International Airport (STL)plane plane TYS - STL
    3h 27m
    $167–767

  2. Drive 493.8 mi

    cheapest
    1. Drive from Knoxville to St. Louis Airport (STL)car car 493.8 mi
    8h 13m
    $91–131

  3. Bus

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus Greyhound US0186 / ...
    12h 17m
    $181–262

  4. Airport Transfer

    1. Take the rideshare from Knoxville to St. Louis-STLrideshare rideshare 493.8 mi
    8h 13m

  5. Drive to Chattanooga Metropolitan Airport, fly

    1. Drive from Knoxville to Chattanooga Metropolitan Airport (CHA)car car
    2. Fly from Chattanooga Metropolitan Airport (CHA) to Lambert–St. Louis International Airport (STL)plane plane CHA - STL
    5h 18m
    $114–577

  6. Drive to Asheville Regional Airport, fly

    1. Drive from Knoxville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Lambert–St. Louis International Airport (STL)plane plane AVL - STL
    5h 50m
    $122–582

  7. Bus via Carbondale

    1. Take the bus from Knoxville to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the bus from Carbondale to St. Louisbus bus
    12h 32m
    $181–272

Mcghee Tyson Airport (TYS) to Lambert–St. Louis International Airport (STL) flights

Calendar130Weekly Planes
Duration4h 58mAverage Duration
Ticket$112Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to St. Louis Airport (STL).ExpandLaunch map view
  • Distance: 417.2 mi
  • Duration: 3h 27m

What companies run services between Knoxville, TN, USA and St. Louis Airport (STL), USA?

Southwest Airlines, Delta, and two other airlines fly from Mcghee Tyson Airport (TYS) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a vehicle from Knoxville to LAMBERT AIRPORT TERMINAL #1 station via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, St Louis Bus Station, and CIVIC CENTER station in around 12h 17m.

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