Rome2Rio

How to get fromKnoxville to Sumterby plane, bus, car, shuttle, or taxi

Find Transport to Sumter

See all options

There are 6 ways to get from Knoxville to Sumter by plane, bus, car, shuttle, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Regional Airport, bus

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Florence Regional Airport (FLO)plane plane TYS - FLO
    2. Take the bus from Florence Bus Station to Sumter Bus Stopbus bus
    5h 51m
    $135–494

  2. Drive 306.5 mi

    cheapest
    1. Drive from Knoxville to Sumtercar car 306.5 mi
    5h 35m
    $56–81

  3. Drive, shuttle, bus

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    4. Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus bus
    5. Take the bus from Charlotte Bus Station to Sumter Bus Stopbus bus
    12h 30m
    $345–392

  4. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Charlotte Douglas International Airport (CLT)plane plane TYS - CLT
    2. Take the bus from Charlotte Bus Station to Sumter Bus Stopbus bus
    6h 4m
    $157–708

  5. Fly to Columbia, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Columbia (CAE)plane plane TYS - CAE
    2. Take the bus from Laurel Sumter East to James E Clyburn Intermodal Transportation Centerbus bus
    7h 16m
    $201–1,071

  6. Drive, shuttle, taxi, bus

    1. Drive from Chilhowee at Holston to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to ASU Peacock Hall Boonetaxi taxi
    4. Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus bus
    5. Take the bus from Charlotte Bus Station to Sumter Bus Stopbus bus
    12h 52m
    $380–457

Mcghee Tyson Airport (TYS) to Florence Regional Airport (FLO) flights

Calendar14Weekly Planes
Duration4h 21mAverage Duration
Ticket$62Cheapest Price
See schedules

Questions & Answers

Map of how to get from Knoxville to Sumter.ExpandLaunch map view
  • Distance: 320.3 mi
  • Duration: 5h 51m

What companies run services between Knoxville, TN, USA and Sumter, SC, USA?

There is no direct connection from Knoxville to Sumter. However, you can take the taxi to Mcghee Tyson Airport (TYS) airport, fly to Florence Regional Airport (FLO), take the taxi to Florence Bus Station, then take the bus to Sumter Bus Stop. Alternatively, you can take a vehicle from Knoxville to Sumter Bus Stop via Hot Springs, Black Bear Resort, Boone, ASU Peacock Hall Boone, Charlotte Airport, Charlotte Douglas Airport, Transit Center- Bay V, Transit Center- Bay E, 4th St & Graham St, and Charlotte Bus Station in around 12h 30m.

Airlines
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound