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How to get fromKnoxville to Sumterby plane, bus, car, or shuttle

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There are 6 ways to get from Knoxville to Sumter by plane, bus, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Regional Airport, bus

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Florence Regional Airport (FLO)plane plane TYS - FLO
    2. Take the bus from Florence Bus Station to Sumter Bus Stopbus bus
    5h 57m
    $130–462

  2. Drive  306.5 mi

    cheapest
    1. Drive from Knoxville to Sumtercar car 306.5 mi
    5h 35m
    $56–81

  3. Drive, shuttle, bus via Charlotte Airport (CLT)

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    4. Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus bus
    5. Take the bus from Charlotte Bus Station to Sumter Bus Stopbus bus
    12h 30m
    $345–384

  4. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Charlotte Douglas International Airport (CLT)plane plane TYS - CLT
    2. Take the bus from Charlotte Bus Station to Sumter Bus Stopbus bus
    5h 53m
    $142–580

  5. Fly to Columbia, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Columbia (CAE)plane plane TYS - CAE
    2. Take the bus from Laurel Sumter East to James E Clyburn Intermodal Transportation Centerbus bus
    7h 20m
    $111–431

  6. Drive, shuttle, bus

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take a shuttle bus from Black Bear Resort to Booneshuttle bus
    4. Take the bus from Boone to Charlottebus bus
    5. Take the bus from Charlotte Bus Station to Sumter Bus Stopbus bus
    12h 44m
    $268–292

Mcghee Tyson Airport (TYS) to Florence Regional Airport (FLO) flights

Calendar19Weekly Planes
Duration3h 56mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

Map of how to get from Knoxville to Sumter.ExpandLaunch map view
  • Distance: 320.3 mi
  • Duration: 5h 57m

What companies run services between Knoxville, TN, USA and Sumter, SC, USA?

There is no direct connection from Knoxville to Sumter. However, you can take the taxi to Mcghee Tyson Airport (TYS) airport, fly to Florence Regional Airport (FLO), take the taxi to Florence Bus Station, then take the bus to Sumter Bus Stop. Alternatively, you can take a vehicle from Knoxville to Sumter Bus Stop via Hot Springs, Black Bear Resort, Boone, ASU Peacock Hall Boone, Charlotte Airport, Charlotte Douglas Airport, Transit Center- Bay V, Transit Center- Bay E, 4th St & Graham St, and Charlotte Bus Station in around 12h 30m.

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