There are 6 ways to get from Knoxville to Tupelo by plane, car, bus (Greyhound), bus, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Golden Triangle Regional Airport, drive
best- Fly from Mcghee Tyson Airport (TYS) to Golden Triangle Regional Airport (GTR)plane TYS - GTR
- Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
4h 43m$128–474Drive 347.3 mi
cheapest- Drive from Knoxville to Tupelocar 347.3 mi
6h 22m$64–92Bus
- Take the bus from Knoxville to Memphis - Summer Avebus Nyc
- Take the bus from Memphis Bus Station to Tupelobus Greyhound US0610
9h 58m$201–279Fly to Tupelo Regional Airport
- Fly from Mcghee Tyson Airport (TYS) to Tupelo Regional Airport (TUP)plane TYS - TUP
6h 10m$151–565Fly to Memphis, bus
- Fly from Mcghee Tyson Airport (TYS) to Memphis (MEM)plane TYS - MEM
- Take the bus from Memphis Bus Station to Tupelobus
5h 44m$185–817Bus via Nashville
- Take the bus from Knoxville to Nashvillebus Nyc
- Take the bus from Nashville Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
11h 4m$190–283
Mcghee Tyson Airport (TYS) to Golden Triangle Regional Airport (GTR) flights
Questions & Answers
The cheapest way to get from Knoxville to Tupelo is to drive which costs $60 - $95 and takes 6h 22m.
The fastest way to get from Knoxville to Tupelo is to fly and drive which takes 4h 43m and costs $120 - $480.
No, there is no direct bus from Knoxville to Tupelo. However, there are services departing from Knoxville and arriving at Tupelo via Memphis Bus Station. The journey, including transfers, takes approximately 9h 58m.
The distance between Knoxville and Tupelo is 384 miles. The road distance is 349.3 miles.
The best way to get from Knoxville to Tupelo without a car is to bus which takes 9h 58m and costs $200 - $280.
It takes approximately 4h 43m to get from Knoxville to Tupelo, including transfers.
Knoxville to Tupelo bus services, operated by Wanda Coach, depart from Knoxville station.
The best way to get from Knoxville to Tupelo is to bus which takes 9h 58m and costs $200 - $280. Alternatively, you can fly, which costs $150 - $600 and takes 6h 10m.
Knoxville to Tupelo bus services, operated by Wanda Coach, arrive at Memphis - Summer Ave station.
Tupelo is 1h behind Knoxville. It is currently 2:50 PM in Knoxville and 1:50 PM in Tupelo.
What companies run services between Knoxville, TN, USA and Tupelo, MS, USA?
You can take a vehicle from Knoxville to Tupelo via Knoxville, Memphis - Summer Ave, Memphis Bus Station, and Tupelo in around 9h 58m. Alternatively, American Airlines, Corporate Flight Management Inc, and two other airlines fly from Mcghee Tyson Airport (TYS) to Tupelo Regional Airport (TUP) 3 times a day.
- Website
- contouraviation.com
Flights from Mcghee Tyson Airport to Tupelo Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 56m
- When
- Every day
- Estimated price
- $140–700
Flights from Mcghee Tyson Airport to Tupelo Regional Airport via Nashville
- Ave. Duration
- 6h 30m
- When
- Monday to Saturday
- Estimated price
- $140–600
Flights from Mcghee Tyson Airport to Tupelo Regional Airport via Atlanta, Nashville
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $80–480
Flights from Mcghee Tyson Airport to Tupelo Regional Airport via Charlotte, Nashville
- Ave. Duration
- 7h 20m
- When
- Thursday and Sunday
- Estimated price
- $95–550
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from Knoxville to Memphis - Summer Ave
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $55–80
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $55–80
Bus from Knoxville to Nashville
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $40–60
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More Questions & Answers
Yes, the driving distance between Knoxville to Tupelo is 349 miles. It takes approximately 6h 22m to drive from Knoxville to Tupelo.
There are 33+ hotels available in Tupelo.