What is the cheapest way to get from Knoxville to Tupelo?

The cheapest way to get from Knoxville to Tupelo is to drive which costs $60 - $95 and takes 6h 22m.

What is the fastest way to get from Knoxville to Tupelo?

The fastest way to get from Knoxville to Tupelo is to fly and bus which takes 5h 44m and costs $190 - $850.

Is there a direct bus between Knoxville and Tupelo?

No, there is no direct bus from Knoxville to Tupelo. However, there are services departing from Knoxville and arriving at Tupelo via Memphis Bus Station. The journey, including transfers, takes approximately 9h 58m.

How far is it from Knoxville to Tupelo?

The distance between Knoxville and Tupelo is 497 miles. The road distance is 349.3 miles.

How do I travel from Knoxville to Tupelo without a car?

The best way to get from Knoxville to Tupelo without a car is to bus which takes 9h 58m and costs $200 - $270.

How long does it take to get from Knoxville to Tupelo?

It takes approximately 9h 58m to get from Knoxville to Tupelo, including transfers.

Where do I catch the Knoxville to Tupelo bus from?

Knoxville to Tupelo bus services, operated by Wanda Coach, depart from Knoxville station.

Where does the Knoxville to Tupelo bus arrive?

Knoxville to Tupelo bus services, operated by Wanda Coach, arrive at Memphis - Summer Ave station.

What is the time difference between Knoxville and Tupelo?

Tupelo is 1h behind Knoxville. It is currently 1:51 AM in Knoxville and 12:51 AM in Tupelo.

Can I drive from Knoxville to Tupelo?

Yes, the driving distance between Knoxville to Tupelo is 349 miles. It takes approximately 6h 22m to drive from Knoxville to Tupelo.

Where can I stay near Tupelo?

There are 33+ hotels available in Tupelo.

Knoxville to Tupelo - 5 ways to travel via bus, car, and plane

How to get fromKnoxville to Tupelo

Travel from

See all options

Search accommodation with Expedia

There are 5 ways to get from Knoxville to Tupelo by bus (Greyhound), car, plane, bus (Greyhound, Flixbus), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Bus
best
1. Take the bus from Knoxville to Memphis - Summer Avebus Nyc
2. Take the bus from Memphis Bus Station to Tupelobus Greyhound US0610
9h 58m
$200–269
Drive 347.3 mi
cheapest
1. Drive from Knoxville to Tupelocar 347.3 mi
6h 22m
$64–92
Fly to Golden Triangle Regional Airport, drive
1. Fly from Mcghee Tyson Airport (TYS) to Golden Triangle Regional Airport (GTR)plane TYS - GTR
2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
6h 3m
$128–474
Bus via Nashville
1. Take the bus from Knoxville to Nashvillebus Nyc
2. Take the bus from Nashville Bus Station to Memphis Bus Stationbus
3. Take the bus from Memphis Bus Station to Tupelobus
11h 4m
$189–263
Fly to Memphis, bus
1. Fly from Mcghee Tyson Airport (TYS) to Memphis (MEM)plane TYS - MEM
2. Take the bus from Memphis Bus Station to Tupelobus
5h 44m
$194–807

Mcghee Tyson Airport (TYS) to Golden Triangle Regional Airport (GTR) flights

21Weekly Planes

6h 2mAverage Duration

$64Cheapest Price

See schedules

Comparing Your Travel Options

Map of how to get from Knoxville to Tupelo.

Launch map view

Distance: 493.7 mi
Duration: 9h 58m

What companies run services between Knoxville, TN, USA and Tupelo, MS, USA?

You can take a vehicle from Knoxville to Tupelo via Knoxville, Memphis - Summer Ave, Memphis Bus Station, and Tupelo in around 9h 58m.

Airlines

Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.