There are 5 ways to get from Knoxville to Winston-Salem by plane, car, shuttle, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Piedmont Triad International Airport
best- Fly from Mcghee Tyson Airport (TYS) to Piedmont Triad International Airport (GSO)plane TYS - GSO
4h 49m$176–790Drive 238.9 mi
cheapest- Drive from Knoxville to Winston-Salemcar 238.9 mi
4h 53m$44–63Drive, shuttle, bus via Charlotte Airport (CLT)
- Drive from Knoxville to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Boone
- Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
11h 20m$336–397Fly to Charlotte Douglas International Airport, bus
- Fly from Mcghee Tyson Airport (TYS) to Charlotte Douglas International Airport (CLT)plane TYS - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
4h 54m$153–713Drive, shuttle, bus
- Drive from Chilhowee at Holston to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Asheville Airport
- Take the bus from Asheville, NC to Winston Salem(Trans Center)bus
12h 8m$341–370
Mcghee Tyson Airport (TYS) to Piedmont Triad International Airport (GSO) flights
Questions & Answers
The cheapest way to get from Knoxville to Winston-Salem is to drive which costs $40 - $65 and takes 4h 53m.
The fastest way to get from Knoxville to Winston-Salem is to fly which takes 4h 49m and costs $170 - $800.
The distance between Knoxville and Winston-Salem is 265 miles. The road distance is 240.3 miles.
It takes approximately 4h 49m to get from Knoxville to Winston-Salem, including transfers.
Yes, the driving distance between Knoxville to Winston-Salem is 240 miles. It takes approximately 4h 53m to drive from Knoxville to Winston-Salem.
There are 142+ hotels available in Winston-Salem.
What companies run services between Knoxville, TN, USA and Winston-Salem, NC, USA?
American Airlines, Delta, and United Airlines fly from Mcghee Tyson Airport (TYS) to Piedmont Triad International Airport (GSO) hourly.
- Website
- aa.com
Flights from Mcghee Tyson Airport to Piedmont Triad International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $100–700
Flights from Mcghee Tyson Airport to Piedmont Triad International Airport via Philadelphia
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Mcghee Tyson Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $85–600
- Website
- delta.com
Flights from Mcghee Tyson Airport to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $140–800
Flights from Mcghee Tyson Airport to Piedmont Triad International Airport via Detroit
- Ave. Duration
- 6h 2m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $210–1,100
Flights from Mcghee Tyson Airport to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 3h 39m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–700
- Website
- united.com
Flights from Mcghee Tyson Airport to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $170–900
- Website
- southwest.com
Flights from Mcghee Tyson Airport to Charlotte Douglas International Airport via Nashville
- Ave. Duration
- 3h 30m
- When
- Sunday
- Estimated price
- $130–750
- Phone
- +1-423-725-5988
- Website
- blackbearresorttn.com
Shuttle from Hot Springs to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- https://blackbearresorttn.com/Shuttle-Service.html
Shuttle from Black Bear Resort to Boone
- Ave. Duration
- 1h
- Frequency
- On demand
- Estimated price
- $86
- Website
- https://blackbearresorttn.com/Shuttle-Service.html
Shuttle from Hot Springs to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- https://blackbearresorttn.com/Shuttle-Service.html
Shuttle from Black Bear Resort to Asheville Airport
- Ave. Duration
- 2h 30m
- Frequency
- On demand
- Estimated price
- $168
- Website
- https://blackbearresorttn.com/Shuttle-Service.html
- Phone
- +1 828-327-2340
- [email protected]
- Website
- hickoryhop.com
Bus from ASU Peacock Hall Boone to Charlotte Airport
- Ave. Duration
- 2h 30m
- Frequency
- Every 4 hours
- Estimated price
- $90–110
- Schedules at
- hickoryhop.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $11–23
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $11–23
- Website
- https://www.greyhound.com/
Bus from Asheville, NC to Winston Salem(Trans Center)
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $22–45
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $7–40
- Website
- https://baronsbus.com
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $7–40
- Website
- https://baronsbus.com
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