There are 4 ways to get from L'Aquila to Isernia by bus, train, train (Trenitalia), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from L'Aquila to Cassinobus 556 / ...
- Take the train from Cassino to Iserniatrain Re
3h 37m€17–29Train (Trenitalia)
- Take the train from L'aquila to Ternitrain Re
- Take the train from Terni to Roma Terminitrain
- Take the train from Roma Termini to Iserniatrain Re
7h 10m€45–88Drive 143.2 km
- Drive from L'Aquila to Iserniacar 143.2 km
2h 30m€23–33Bus
- Take the bus from L'Aquila to Roma, Autostazione Tiburtinabus
- Take the bus from Roma, Autostazione Tiburtina to Iserniabus Rome Tiburtina
4h 45m€18–38
L'Aquila to Isernia by bus and train
Questions & Answers
The cheapest way to get from L'Aquila to Isernia is to bus and train which costs €17 - €29 and takes 3h 37m.
The fastest way to get from L'Aquila to Isernia is to drive which takes 2h 30m and costs €22 - €35.
No, there is no direct bus from L'Aquila to Isernia. However, there are services departing from L'Aquila and arriving at Isernia via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 4h 45m.
No, there is no direct train from L'Aquila to Isernia. However, there are services departing from L'aquila and arriving at Isernia via Terni and Roma Termini. The journey, including transfers, takes approximately 7h 10m.
The distance between L'Aquila and Isernia is 184 km. The road distance is 143.2 km.
The best way to get from L'Aquila to Isernia without a car is to bus and train which takes 3h 37m and costs €17 - €29.
It takes approximately 3h 37m to get from L'Aquila to Isernia, including transfers.
L'Aquila to Isernia bus services, operated by TUA Società Unica Abruzzese di Trasporto, depart from L'Aquila station.
L'Aquila to Isernia train services, operated by Trenitalia, depart from L'aquila station.
The best way to get from L'Aquila to Isernia is to train which takes 7h 10m and costs €45 - €90. Alternatively, you can bus, which costs €18 - €40 and takes 4h 45m.
What companies run services between L'Aquila, Italy and Isernia, Italy?
You can take a train from L'aquila to Isernia via Terni and Roma Termini in around 7h 10m. Alternatively, you can take a bus from L'Aquila to Isernia via Roma, Autostazione Tiburtina in around 4h 45m.
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Cassino to Isernia
- Ave. Duration
- 48 min
- Frequency
- Every 3 hours
- Estimated price
- €6–11
- Website
- https://www.trenitalia.com/en.html
Train from L'aquila to Terni
- Ave. Duration
- 1h 57m
- Frequency
- Hourly
- Estimated price
- €12–20
- Website
- https://www.trenitalia.com/en.html
Train from Terni to Roma Termini
- Ave. Duration
- 1h 38m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 16m
- Frequency
- Every 3 hours
- Estimated price
- €23–40
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Terni to Roma Termini
- Ave. Duration
- 1h 12m
- Frequency
- Every 4 hours
- Estimated price
- €10–21
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Terni to Roma Termini
- Ave. Duration
- 59 min
- Frequency
- 3 times a day
- Estimated price
- €14–28
- Schedules at
- trenitalia.com
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from L'Aquila to Cassino
- Ave. Duration
- 1h 49m
- Frequency
- Twice daily
- Estimated price
- €11–18
- Website
- https://www.flixbus.co.uk
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- €14–24
- Website
- https://www.flixbus.co.uk
- Phone
- 800.14.28.80
- [email protected]
- Website
- tuabruzzo.it
Bus from L'Aquila to Roma, Autostazione Tiburtina
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- €10–14
- Schedules at
- tuabruzzo.it
- .
- €10–14
- Phone
- +39 0874 64744
- [email protected]
- Website
- atm-molise.it
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
More Questions & Answers
L'Aquila to Isernia bus services, operated by TUA Società Unica Abruzzese di Trasporto, arrive at Roma, Autostazione Tiburtina station.
L'Aquila to Isernia train services, operated by Trenitalia, arrive at Terni station.
Yes, the driving distance between L'Aquila to Isernia is 143 km. It takes approximately 2h 30m to drive from L'Aquila to Isernia.
Book your L'Aquila to Isernia train tickets online with Omio.
Book your L'Aquila to Isernia bus tickets online with Omio.
There are 478+ hotels available in Isernia.




















