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How to get fromLa Crosse (Station) to Milwaukeeby train (Amtrak), bus, car, or plane

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There are 5 ways to get from La Crosse (Station) to Milwaukee by train (Amtrak), bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from La Crosse Amtrak Station to Milwaukeetrain train Empire Builder / ...
    3h 24m
    $66–137
  2. Drive 209.7 mi

    cheapest
    1. Drive from La Crosse (Station) to Milwaukeecar car 209.7 mi
    3h 29m
    $39–56
  3. Bus

    1. Take the bus from La Crosse to Milwaukee, WI - Amtrakbus bus Minneapolis / ...
    4h 50m
    $55–80
  4. Fly to General Mitchell International Airport

    1. Fly from La Crosse (LSE) to General Mitchell International Airport (MKE)plane plane LSE - MKE
    5h 20m
    $83–451
  5. Fly to Chicago O'Hare International Airport, bus

    1. Fly from La Crosse (LSE) to Chicago O'Hare International Airport (ORD)plane plane LSE - ORD
    2. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    4h 4m
    $59–286

La Crosse (Station) to Milwaukee by bus

Calendar21Weekly Buses
Duration4h 50mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

What companies run services between La Crosse (Station), WI, USA and Milwaukee, WI, USA?

Amtrak operates a train from La Crosse Amtrak Station to Milwaukee 3 times a day. Tickets cost $60–130 and the journey takes 3h 20m. Alternatively, Jefferson Lines operates a bus from La Crosse to Milwaukee, WI - Amtrak 3 times a day. Tickets cost $55–80 and the journey takes 4h 50m.

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