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How to get fromLa Crosse to Ann Arborby train (Amtrak), bus (Flixbus), car, plane, bus, bus (Amtrak), or train

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There are 9 ways to get from La Crosse to Ann Arbor by train (Amtrak), bus (Flixbus), car, plane, bus, bus (Amtrak), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train Empire Builder / ...
    2. Take the train from Chicago Union Station to Ann Arbor Amtrak Stationtrain train Wolverine
    10h 22m
    $166–345

  2. Drive 521.2 mi

    cheapest
    1. Drive from La Crosse to Ann Arborcar car 521.2 mi
    8h 40m
    $96–138

  3. Bus

    1. Take the bus from La Crosse to Milwaukee, WI - Amtrakbus bus Minneapolis / ...
    2. Take the bus from Milwaukee Intermodal Station to Ann Arborbus bus FlixBus 2550
    12h 25m
    $108–170

  4. Fly La Crosse to Detroit, bus

    1. Fly from La Crosse (LSE) to Detroit (DTW)plane plane LSE - DTW
    2. Take the bus from Detroit Metro Airport to Ann Arbor- Blake Transit Ctr., MIbus bus
    6h 16m
    $102–471

  5. Bus via Chicago

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Union Station to Ann Arbor Amtrak Stationbus bus
    13h 12m
    $148–238

  6. Bus to Dane County Regional Airport-Truax Field, fly to Detroit, bus

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Detroit (DTW)plane plane MSN - DTW
    3. Take the bus from Detroit Metro Airport to Ann Arbor- Blake Transit Ctr., MIbus bus
    8h 25m
    $138–630

  7. Train to Minneapolis–Saint Paul International Airport, fly to Detroit, bus

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Detroit (DTW)plane plane MSP - DTW
    3. Take the bus from Detroit Metro Airport to Ann Arbor- Blake Transit Ctr., MIbus bus
    8h 11m
    $523–1,308

  8. Fly La Crosse to Bishop International Airport, bus

    1. Fly from La Crosse (LSE) to Bishop International Airport (FNT)plane plane LSE - FNT
    2. Take the bus from Flint Station to East Lansing Michigan Flyerbus bus
    3. Take the bus from East Lansing, MI to Ann Arbor- Blake Transit Ctr., MIbus bus
    8h 51m
    $125–444

  9. Bus to Appleton International Airport, fly to Detroit, bus

    1. Take the bus from La Crosse Grand River Station to Appleton Valley Transitbus bus
    2. Fly from Appleton International Airport (ATW) to Detroit (DTW)plane plane ATW - DTW
    3. Take the bus from Detroit Metro Airport to Ann Arbor- Blake Transit Ctr., MIbus bus
    8h 54m
    $119–467

La Crosse to Ann Arbor by train (Amtrak)

Calendar21Weekly Trains
Duration10h 22mAverage Duration
Ticket$166Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Ann Arbor.ExpandLaunch map view
  • Distance: 522.3 mi
  • Duration: 10h 22m

What companies run services between La Crosse, WI, USA and Ann Arbor, MI, USA?

You can take a train from La Crosse Amtrak Station to Ann Arbor Amtrak Station via Chicago Union Station in around 10h 22m. Alternatively, you can take a bus from La Crosse to Ann Arbor via Milwaukee Intermodal Station in around 12h 25m.

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