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How to get fromLa Crosse to Bostonby plane, bus, train (Amtrak), bus (Greyhound, Flixbus), car, or train

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There are 6 ways to get from La Crosse to Boston by plane, bus, train (Amtrak), bus (Greyhound, Flixbus), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Manchester Airport, bus

    best
    1. Fly from La Crosse (LSE) to Manchester Airport (MHT)plane plane LSE - MHT
    2. Take the bus from Boston Manchester Airport to Bostonbus bus
    9h 57m
    $122–495

  2. Fly to Theodore Francis Green State Airport, train

    cheapest
    1. Fly from La Crosse (LSE) to Theodore Francis Green State Airport (PVD)plane plane LSE - PVD
    2. Take the train from TF Green Airport to South Stationtrain train
    8h 15m
    $97–397

  3. Train (Amtrak)

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train Empire Builder / ...
    2. Take the train from Chicago Union Station to Bostontrain train Lake Shore Limited
    28h 10m
    $705–1,138

  4. Bus

    1. Take the bus from La Crosse to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Newark Penn Stationbus bus
    4. Take the bus from Newark Penn Station to Bostonbus bus
    32h 55m
    $248–388

  5. Drive  1,261.3 mi

    1. Drive from La Crosse to Bostoncar car 1,261.3 mi
    21h 30m
    $231–333

  6. Bus, train

    1. Take the bus from La Crosse to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Bostontrain train
    29h 58m
    $615–1,013

La Crosse to Boston by train (Amtrak)

Calendar7Weekly Trains
Duration28h 10mAverage Duration
Ticket$705Cheapest Price
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Comparing Your Travel Options

Map of how to get from La Crosse to Boston.ExpandLaunch map view
  • Distance: 1,053.3 mi
  • Duration: 9h 57m

What companies run services between La Crosse, WI, USA and Boston, MA, USA?

You can take a train from La Crosse Amtrak Station to Boston via Chicago Union Station in around 28h 10m. Alternatively, you can take a bus from La Crosse to Boston via Milwaukee, Milwaukee Intermodal Station, Chicago Bus Station, and Newark Penn Station in around 32h 55m.

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