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How to get fromLa Crosse to Champaignby train (Amtrak), bus (Greyhound, Flixbus), car, plane, or bus (Flixbus)

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There are 5 ways to get from La Crosse to Champaign by train (Amtrak), bus (Greyhound, Flixbus), car, plane, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train Empire Builder / ...
    2. Take the train from Chicago Union Station to Champaign-Urbanatrain train Illini / ...
    8h 39m
    $225–348

  2. Drive  384.2 mi

    cheapest
    1. Drive from La Crosse to Champaigncar car 384.2 mi
    6h 17m
    $71–102

  3. Bus via Milwaukee

    1. Take the bus from La Crosse to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Downtown Chicago to Illinois Terminalbus bus
    10h 15m
    $89–133

  4. Fly

    1. Fly from La Crosse (LSE) to University Of Illinois Willard Airport (CMI)plane plane LSE - CMI
    5h 36m
    $86–374

  5. Bus

    1. Take the bus from La Crosse to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago to Champaign Intermodal Trans Ctrbus bus
    10h 55m
    $89–150

La Crosse to Champaign by train (Amtrak)

Calendar21Weekly Trains
Duration8h 39mAverage Duration
Ticket$225Cheapest Price
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Comparing Your Travel Options

Map of how to get from La Crosse to Champaign.ExpandLaunch map view
  • Distance: 408.1 mi
  • Duration: 8h 39m

What companies run services between La Crosse, WI, USA and Champaign, IL, USA?

You can take a train from La Crosse Amtrak Station to Champaign-Urbana via Chicago Union Station in around 8h 39m. Alternatively, you can take a bus from La Crosse to Illinois Terminal via Milwaukee, Milwaukee Intermodal Station, Chicago Bus Station, and Downtown Chicago in around 10h 15m.

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