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How to get fromLa Crosse to Charlotteby plane, bus, train (Amtrak), car, or bus (Amtrak, Greyhound)

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There are 6 ways to get from La Crosse to Charlotte by plane, bus, train (Amtrak), car, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from La Crosse

    best
    1. Fly from La Crosse (LSE) to Charlotte Douglas International Airport (CLT)plane plane LSE - CLT
    5h 45m
    $141–674

  2. Bus

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago to N Wilson Rd & Ferrell Pl - Columbusbus bus
    4. Take the bus from Columbus to Charlottebus bus
    27h 33m

  3. Train (Amtrak)

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Charlotte Amtrak Stationtrain train
    34h 32m
    $492–1,043

  4. Drive 1,009.4 mi

    1. Drive from La Crosse to Charlottecar car 1,009.4 mi
    18h 7m
    $185–267

  5. Bus to Dane County Regional Airport-Truax Field, fly

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Charlotte Douglas International Airport (CLT)plane plane MSN - CLT
    7h 59m
    $197–863

  6. Bus via Toledo

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Union Station to Toledobus bus
    4. Take the bus from Toledo Bus Stop to Charlotte Bus Stationbus bus
    27h 54m
    $253–428

La Crosse (LSE) to Charlotte Douglas International Airport (CLT) flights

Calendar35Weekly Planes
Duration6h 17mAverage Duration
Ticket$125Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Charlotte.ExpandLaunch map view
  • Distance: 825.3 mi
  • Duration: 5h 45m

What companies run services between La Crosse, WI, USA and Charlotte, NC, USA?

American Airlines and United Airlines fly from La Crosse (LSE) to Charlotte Douglas International Airport (CLT) 5 times a day. Alternatively, you can take a bus from La Crosse to Charlotte via 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, Chicago, and Columbus in around 27h 33m.

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