There are 5 ways to get from La Crosse to Cleveland by plane, train (Amtrak), bus (Greyhound, Flixbus), car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from La Crosse (LSE) to Cleveland-Hopkins International Airport (CLE)plane LSE - CLE
5h 39m$101–504Bus via Chicago
cheapest- Take the bus from La Crosse to Milwaukeebus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
- Take the bus from Chicago to Clevelandbus
14h 20m$97–179Train (Amtrak)
- Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain Empire Builder / ...
- Take the train from Chicago Union Station to Cleveland Amtraktrain Floridian / ...
12h 13m$165–365Drive 623.7 mi
- Drive from La Crosse to Clevelandcar 623.7 mi
10h 23m$114–165Bus
- Take the bus from La Crosse Grand River Station to Appleton Valley Transitbus
- Take the bus from Appleton Transit Center to Detroit Bus Stationbus
- Take the bus from Detroit Bus Station to Cleveland Bus Stationbus
19h 56m$125–196
La Crosse to Cleveland by train (Amtrak)
Questions & Answers
The cheapest way to get from La Crosse to Cleveland is to drive which costs $110 - $170 and takes 10h 23m.
The fastest way to get from La Crosse to Cleveland is to fly which takes 5h 39m and costs $100 - $550.
No, there is no direct bus from La Crosse to Cleveland. However, there are services departing from La Crosse and arriving at Cleveland via Milwaukee Intermodal Station and Chicago. The journey, including transfers, takes approximately 14h 20m.
No, there is no direct train from La Crosse station to Cleveland. However, there are services departing from La Crosse Amtrak Station and arriving at Cleveland Amtrak via Chicago Union Station. The journey, including transfers, takes approximately 12h 13m.
The distance between La Crosse and Cleveland is 529 miles. The road distance is 627.3 miles.
The best way to get from La Crosse to Cleveland without a car is to train which takes 12h 13m and costs $160 - $370.
It takes approximately 5h 39m to get from La Crosse to Cleveland, including transfers.
La Crosse to Cleveland bus services, operated by Jefferson Lines, depart from La Crosse station.
La Crosse to Cleveland train services, operated by Amtrak, depart from La Crosse Amtrak Station.
The best way to get from La Crosse to Cleveland is to fly which takes 5h 39m and costs $100 - $550. Alternatively, you can train, which costs $160 - $370 and takes 12h 13m, you could also bus via Chicago, which costs $95 - $180 and takes 14h 20m.
What companies run services between La Crosse, WI, USA and Cleveland, OH, USA?
United Airlines and American Airlines fly from La Crosse (LSE) to Cleveland-Hopkins International Airport (CLE) 4 times a day. Alternatively, you can take a train from La Crosse Amtrak Station to Cleveland Amtrak via Chicago Union Station in around 12h 13m.
- Website
- aa.com
Flights from La Crosse to Cleveland-Hopkins International Airport via Chicago O'Hare
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $80–480
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from La Crosse Amtrak Station to Chicago Union Station
- Ave. Duration
- 5h 8m
- Frequency
- 3 times a day
- Estimated price
- $75–170
- Website
- Amtrak
Train from Chicago Union Station to Cleveland Amtrak
- Ave. Duration
- 6h 5m
- Frequency
- 3 times a day
- Estimated price
- $90–200
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from La Crosse to Milwaukee
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
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More Questions & Answers
La Crosse to Cleveland bus services, operated by Jefferson Lines, arrive at Milwaukee station.
Cleveland is 1h ahead of La Crosse. It is currently 12:37 AM in La Crosse and 1:37 AM in Cleveland.
La Crosse to Cleveland train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between La Crosse to Cleveland is 627 miles. It takes approximately 10h 23m to drive from La Crosse to Cleveland.
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