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How to get fromLa Crosse to Columbusby plane, train, bus, car, or bus (Flixbus)

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There are 6 ways to get from La Crosse to Columbus by plane, train, bus, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from La Crosse (LSE) to John Glenn Columbus International Airport (CMH)plane plane LSE - CMH
    5h 21m
    $110–574

  2. Drive 590.4 mi

    cheapest
    1. Drive from La Crosse to Columbuscar car 590.4 mi
    10h 55m
    $108–156

  3. Train, bus

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train Empire Builder / ...
    2. Take the bus from Chicago Bus Station to Columbusbus bus FlixBus 2511 / ...
    13h 37m
    $141–270

  4. Train, bus via Toledo

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Toledotrain train
    3. Take the bus from Toledo to Columbus - Mound Stbus bus
    13h 57m
    $176–370

  5. Bus

    1. Take the bus from La Crosse to Milwaukeebus bus Jefferson Lines 965
    2. Take the bus from Milwaukee Intermodal Station to Columbusbus bus FlixBus 2511
    14h 40m
    $120–195

  6. Bus via Chicago

    1. Take the bus from La Crosse to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Bus Station to Columbusbus bus
    15h 35m
    $120–203

La Crosse to Columbus by train, foot, and bus

Calendar16Weekly Services
Duration13h 37mAverage Duration
Ticket$141Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Columbus.ExpandLaunch map view
  • Distance: 527 mi
  • Duration: 5h 21m

What companies run services between La Crosse, WI, USA and Columbus, OH, USA?

American Airlines and United Airlines fly from La Crosse (LSE) to John Glenn Columbus International Airport (CMH) 3 times a day. Alternatively, you can take a bus from La Crosse to Columbus via Milwaukee and Milwaukee Intermodal Station in around 14h 40m.

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