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How to get fromLa Crosse to Denverby plane, train (Amtrak), bus (Greyhound), car, train, or bus

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There are 9 ways to get from La Crosse to Denver by plane, train (Amtrak), bus (Greyhound), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from La Crosse

    best
    1. Fly from La Crosse (LSE) to Denver (DEN)plane plane LSE - DEN
    6h 54m
    $128–521

  2. Train (Amtrak)

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train Empire Builder / ...
    2. Take the train from Chicago Union Station to Denvertrain train California Zephyr
    25h 4m
    $422–884

  3. Bus

    1. Take the bus from La Crosse to St. Paulbus bus
    2. Take the bus from Saint Paul Union Depot to Des Moinesbus bus
    3. Take the bus from Des Moines to Denver Union Stationbus bus
    25h 5m
    $189–346

  4. Drive 893.2 mi

    1. Drive from La Crosse to Denvercar car 893.2 mi
    15h 15m
    $163–236

  5. Train to Minneapolis–Saint Paul International Airport, fly

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Denver (DEN)plane plane MSP - DEN
    7h 23m
    $164–428

  6. Bus to Dane County Regional Airport-Truax Field, fly

    1. Take the bus from University of Wisconsin - La Crosse to UW-Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Denver (DEN)plane plane MSN - DEN
    8h 16m
    $174–670

  7. Bus to Rochester, fly

    1. Take the bus from La Crosse to Rochester, MNbus bus
    2. Fly from Rochester (RST) to Denver (DEN)plane plane RST - DEN
    8h 52m
    $189–889

  8. Bus to Appleton International Airport, fly

    1. Take the bus from La Crosse Grand River Station to Appleton Valley Transitbus bus
    2. Fly from Appleton International Airport (ATW) to Denver (DEN)plane plane ATW - DEN
    9h 2m
    $150–507

  9. Bus via Sioux Falls

    1. Take the bus from La Crosse to Minneapolisbus bus
    2. Take the bus from Minneapolis to Sioux Fallsbus bus
    3. Take the bus from Sioux Falls to Omahabus bus
    4. Take the bus from Omaha, NE to Denverbus bus
    26h 15m
    $301–419

La Crosse to Denver by train (Amtrak)

Calendar7Weekly Trains
Duration25h 4mAverage Duration
Ticket$422Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Denver.ExpandLaunch map view
  • Distance: 773 mi
  • Duration: 6h 54m

What companies run services between La Crosse, WI, USA and Denver, CO, USA?

United Airlines and American Airlines fly from La Crosse (LSE) to Denver (DEN) every 4 hours. Alternatively, you can take a train from La Crosse Amtrak Station to Denver via Chicago Union Station in around 25h 4m.

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