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How to get fromLa Crosse to Destinby plane, train, bus, taxi, or car

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There are 10 ways to get from La Crosse to Destin by plane, train, bus, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly La Crosse to Destin–Fort Walton Beach Airport

    best
    1. Fly from La Crosse (LSE) to Destin–Fort Walton Beach Airport (VPS)plane plane LSE - VPS
    5h 34m
    $153–526

  2. Train, bus, taxi

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    4. Take the bus from Gulfport to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    32h 32m
    $547–1,053

  3. Bus, taxi

    1. Take the bus from La Crosse to Milwaukee, WI - Amtrakbus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to La Grange Bus Stationbus bus
    5. Take the bus from La Grange Bus Station to Mobilebus bus
    6. Take the bus from Loxley to Crestviewbus bus
    7. Take the taxi from Crestview to Destintaxi taxi
    32h 51m
    $382–592

  4. Drive 1,159.7 mi

    1. Drive from La Crosse to Destincar car 1,159.7 mi
    20h 17m
    $212–306

  5. Fly La Crosse to Northwest Florida Beaches International Airport, taxi

    1. Fly from La Crosse (LSE) to Northwest Florida Beaches International Airport (ECP)plane plane LSE - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    6h 13m
    $253–651

  6. Fly La Crosse to Pensacola International Airport, taxi

    1. Fly from La Crosse (LSE) to Pensacola International Airport (PNS)plane plane LSE - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    6h 14m
    $223–581

  7. Train to Minneapolis–Saint Paul International Airport, fly to Destin–Fort Walton Beach Airport

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Destin–Fort Walton Beach Airport (VPS)plane plane MSP - VPS
    7h 39m
    $194–692

  8. Bus to Dane County Regional Airport-Truax Field, fly to Destin–Fort Walton Beach Airport

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Destin–Fort Walton Beach Airport (VPS)plane plane MSN - VPS
    10h 1m
    $204–715

  9. Bus to Rochester, fly to Destin–Fort Walton Beach Airport

    1. Take the bus from La Crosse to Rochester, MNbus bus
    2. Fly from Rochester (RST) to Destin–Fort Walton Beach Airport (VPS)plane plane RST - VPS
    9h 51m
    $282–1,015

  10. Bus, taxi via Madison

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Train Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Mobile Bus Stationbus bus
    5. Take the bus from Mobile to Crestviewbus bus
    6. Take the taxi from Crestview to Destintaxi taxi
    36h 37m
    $433–623

La Crosse (LSE) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar7Weekly Planes
Duration4h 53mAverage Duration
Ticket$97Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Destin.ExpandLaunch map view
  • Distance: 982.7 mi
  • Duration: 5h 34m

What companies run services between La Crosse, WI, USA and Destin, FL, USA?

American Airlines flies from La Crosse (LSE) to Destin–Fort Walton Beach Airport (VPS) once daily.

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