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How to get fromLa Crosse to Destinby plane, taxi, train, bus, or car

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There are 10 ways to get from La Crosse to Destin by plane, taxi, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly La Crosse to Northwest Florida Beaches International Airport, taxi

    best
    1. Fly from La Crosse (LSE) to Northwest Florida Beaches International Airport (ECP)plane plane LSE - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    6h 16m
    $248–661

  2. Fly La Crosse to Destin–Fort Walton Beach Airport

    cheapest
    1. Fly from La Crosse (LSE) to Destin–Fort Walton Beach Airport (VPS)plane plane LSE - VPS
    5h 39m
    $148–536

  3. Train, bus, taxi

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    4. Take the bus from Gulfport to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    32h 32m
    $451–925

  4. Bus, taxi via Milwaukee

    1. Take the bus from La Crosse to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to La Grange Bus Stationbus bus
    5. Take the bus from La Grange Bus Station to Mobilebus bus
    6. Take the bus from Loxley to Crestviewbus bus
    7. Take the taxi from Crestview to Destintaxi taxi
    33h 18m
    $367–538

  5. Drive  1,158.9 mi

    1. Drive from La Crosse to Destincar car 1,158.9 mi
    20h 20m
    $212–306

  6. Fly La Crosse to Pensacola International Airport, taxi

    1. Fly from La Crosse (LSE) to Pensacola International Airport (PNS)plane plane LSE - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    6h 54m
    $208–551

  7. Train to Minneapolis–Saint Paul International Airport, fly to Destin–Fort Walton Beach Airport

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Destin–Fort Walton Beach Airport (VPS)plane plane MSP - VPS
    7h 39m
    $184–732

  8. Bus to Dane County Regional Airport-Truax Field, fly to Destin–Fort Walton Beach Airport

    1. Take the bus from La Crosse to Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Destin–Fort Walton Beach Airport (VPS)plane plane MSN - VPS
    9h 21m
    $201–760

  9. Bus to Rochester, fly to Destin–Fort Walton Beach Airport

    1. Take the bus from La Crosse to Rochesterbus bus
    2. Fly from Rochester (RST) to Destin–Fort Walton Beach Airport (VPS)plane plane RST - VPS
    9h 3m
    $164–604

  10. Bus, taxi

    1. Take the bus from La Crosse to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Train Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Opelika 4th Street Stationbus bus
    5. Take the bus from Opelika 4th Street Station to Mobilebus bus
    6. Take the bus from Loxley to Crestviewbus bus
    7. Take the taxi from Crestview to Destintaxi taxi
    34h 52m
    $381–568

La Crosse (LSE) to Northwest Florida Beaches International Airport (ECP) flights

Calendar22Weekly Planes
Duration7h 14mAverage Duration
Ticket$93Cheapest Price
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Comparing Your Travel Options

Map of how to get from La Crosse to Destin.ExpandLaunch map view
  • Distance: 1,040 mi
  • Duration: 6h 16m

What companies run services between La Crosse, WI, USA and Destin, FL, USA?

American Airlines and Allegiant Air fly from La Crosse (LSE) to Destin–Fort Walton Beach Airport (VPS) twice a week.

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