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How to get fromLa Crosse to Detroitby plane, train (Amtrak), bus (Flixbus), car, bus, train, or bus (Amtrak)

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There are 7 ways to get from La Crosse to Detroit by plane, train (Amtrak), bus (Flixbus), car, bus, train, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from La Crosse

    best
    1. Fly from La Crosse (LSE) to Detroit (DTW)plane plane LSE - DTW
    5h 37m
    $95–453

  2. Train (Amtrak)

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train Empire Builder / ...
    2. Take the train from Chicago Union Station to Detroittrain train Wolverine
    11h 28m
    $182–374

  3. Bus

    1. Take the bus from University of Wisconsin - La Crosse to Milwaukee, WI - Amtrakbus bus Minneapolis / ...
    2. Take the bus from Milwaukee Intermodal Station to Detroit Bus Stationbus bus FlixBus 2550
    13h 5m
    $113–180

  4. Drive 561.8 mi

    1. Drive from La Crosse to Detroitcar car 561.8 mi
    9h 18m
    $103–149

  5. Bus to Dane County Regional Airport-Truax Field, fly

    1. Take the bus from University of Wisconsin - La Crosse to UW-Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Detroit (DTW)plane plane MSN - DTW
    7h 36m
    $131–612

  6. Train to Minneapolis–Saint Paul International Airport, fly

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Detroit (DTW)plane plane MSP - DTW
    7h 39m
    $516–1,290

  7. Bus via Chicago

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Union Station to Detroitbus bus
    14h 48m
    $163–258

La Crosse to Detroit by train (Amtrak)

Calendar21Weekly Trains
Duration11h 28mAverage Duration
Ticket$182Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Detroit.ExpandLaunch map view
  • Distance: 444.7 mi
  • Duration: 5h 37m

What companies run services between La Crosse, WI, USA and Detroit, MI, USA?

American Airlines and United Airlines fly from La Crosse (LSE) to Detroit (DTW) once daily. Alternatively, you can take a train from La Crosse Amtrak Station to Detroit via Chicago Union Station in around 11h 28m.

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